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    Racgap1 Rac GTPase activating protein 1 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100721177, updated on 3-Apr-2024

    Summary

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    Gene symbol
    Racgap1
    Gene description
    Rac GTPase activating protein 1
    See related
    Ensembl:ENSCPOG00000004383
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Racgap1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947491.1 (41505797..41540627, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176410.1 (49627886..49656040)

    NW_026947491.1Genomic Context describing neighboring genes Neighboring gene aquaporin 5 Neighboring gene aquaporin 6 Neighboring gene acid sensing ion channel subunit 1 Neighboring gene small ribosomal subunit protein eS28-like Neighboring gene uncharacterized LOC134477304 Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic spindle midzone assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of centralspindlin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle midzone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rac GTPase-activating protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947491.1 Reference mCavPor4.1

      Range
      41505797..41540627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063254719.1 → XP_063110789.1  rac GTPase-activating protein 1

      UniProtKB/TrEMBL
      H0V313

    2. XM_063254721.1 → XP_063110791.1  rac GTPase-activating protein 1

      UniProtKB/TrEMBL
      H0V313

    3. XM_003475789.5 → XP_003475837.1  rac GTPase-activating protein 1

      See identical proteins and their annotated locations for XP_003475837.1

      UniProtKB/TrEMBL
      H0V313
      Conserved Domains (2) summary
      cd00029
      Location:287 → 335
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP_MgcRacGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin ...

    4. XM_013159522.3 → XP_013014976.1  rac GTPase-activating protein 1

      See identical proteins and their annotated locations for XP_013014976.1

      UniProtKB/TrEMBL
      H0V313
      Related
      ENSCPOP00000003956.2
      Conserved Domains (2) summary
      cd00029
      Location:287 → 335
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP_MgcRacGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin ...

    5. XM_063254720.1 → XP_063110790.1  rac GTPase-activating protein 1

      UniProtKB/TrEMBL
      H0V313

    6. XM_063254722.1 → XP_063110792.1  rac GTPase-activating protein 1

      UniProtKB/TrEMBL
      H0V313
    Nucleotide Protein
    Heading Accession and Version

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