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    Mapkbp1 mitogen-activated protein kinase binding protein 1 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100721000, updated on 10-Oct-2024

    Summary

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    Gene symbol
    Mapkbp1
    Gene description
    mitogen-activated protein kinase binding protein 1
    See related
    Ensembl:ENSCPOG00000022051
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Mapkbp1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947489.1 (28640193..28700379, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176409.1 (27351540..27409788)

    NW_026947489.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134476399 Neighboring gene spectrin beta, non-erythrocytic 5 Neighboring gene bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 Neighboring gene MAX dimerization protein MGA Neighboring gene TYRO3 protein tyrosine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947489.1 Reference mCavPor4.1

      Range
      28640193..28700379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013158747.3 → XP_013014201.1  mitogen-activated protein kinase-binding protein 1 isoform X1

      See identical proteins and their annotated locations for XP_013014201.1

      UniProtKB/TrEMBL
      H0WA60
      Conserved Domains (3) summary
      sd00039
      Location:526 → 566
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:350 → 732
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl26464
      Location:1077 → 1483
      Atrophin-1; Atrophin-1 family

    2. XM_013158745.3 → XP_013014199.1  mitogen-activated protein kinase-binding protein 1 isoform X1

      See identical proteins and their annotated locations for XP_013014199.1

      UniProtKB/TrEMBL
      H0WA60
      Conserved Domains (3) summary
      sd00039
      Location:526 → 566
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:350 → 732
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl26464
      Location:1077 → 1483
      Atrophin-1; Atrophin-1 family

    3. XM_013158743.3 → XP_013014197.1  mitogen-activated protein kinase-binding protein 1 isoform X1

      See identical proteins and their annotated locations for XP_013014197.1

      UniProtKB/TrEMBL
      H0WA60
      Conserved Domains (3) summary
      sd00039
      Location:526 → 566
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:350 → 732
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl26464
      Location:1077 → 1483
      Atrophin-1; Atrophin-1 family

    4. XM_063250242.1 → XP_063106312.1  mitogen-activated protein kinase-binding protein 1 isoform X1

    5. XM_063250241.1 → XP_063106311.1  mitogen-activated protein kinase-binding protein 1 isoform X1

    6. XM_013158750.3 → XP_013014204.1  mitogen-activated protein kinase-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      H0WA60
      Related
      ENSCPOP00000019871.2
      Conserved Domains (3) summary
      COG2319
      Location:229 → 720
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:520 → 560
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:84 → 422
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    7. XM_013158749.3 → XP_013014203.1  mitogen-activated protein kinase-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      H0WA60
      Conserved Domains (3) summary
      COG2319
      Location:229 → 720
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:520 → 560
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:84 → 422
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    8. XM_013158748.3 → XP_013014202.1  mitogen-activated protein kinase-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      H0WA60
      Conserved Domains (3) summary
      COG2319
      Location:244 → 736
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:526 → 566
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:350 → 732
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    9. XM_023567540.2 → XP_023423308.1  mitogen-activated protein kinase-binding protein 1 isoform X6

      UniProtKB/TrEMBL
      H0WA60
      Conserved Domains (3) summary
      sd00039
      Location:526 → 566
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:350 → 732
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl26464
      Location:756 → 1192
      Atrophin-1; Atrophin-1 family

    10. XM_063250244.1 → XP_063106314.1  mitogen-activated protein kinase-binding protein 1 isoform X5

    Nucleotide Protein
    Heading Accession and Version

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