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    Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100720693, updated on 3-Apr-2024

    Summary

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    Gene symbol
    Ezh1
    Gene description
    enhancer of zeste 1 polycomb repressive complex 2 subunit
    See related
    Ensembl:ENSCPOG00000012533
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Ezh1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947489.1 (94477834..94498889, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176366.1 (12367231..12388245, complement)

    NW_026947489.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology, MyTH4 and FERM domain containing H3 Neighboring gene contactin associated protein 1 Neighboring gene C-C motif chemokine receptor 10 Neighboring gene uncharacterized LOC134476561 Neighboring gene receptor activity modifying protein 2 Neighboring gene vacuolar protein sorting 25 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone H3K27 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heterochromatin formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ESC/E(Z) complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase EZH1
    Names
    enhancer of zeste homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947489.1 Reference mCavPor4.1

      Range
      94477834..94498889 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013149669.3 → XP_013005123.1  histone-lysine N-methyltransferase EZH1

      See identical proteins and their annotated locations for XP_013005123.1

      UniProtKB/TrEMBL
      H0VLN2
      Conserved Domains (5) summary
      smart00717
      Location:433 → 474
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      smart00317
      Location:613 → 734
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG2940
      Location:463 → 727
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      cd00167
      Location:433 → 474
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam11616
      Location:39 → 67
      EZH2_WD-Binding; WD repeat binding protein EZH2

    2. XM_063251608.1 → XP_063107678.1  histone-lysine N-methyltransferase EZH1

      UniProtKB/TrEMBL
      H0VLN2

    3. XM_063251605.1 → XP_063107675.1  histone-lysine N-methyltransferase EZH1

      UniProtKB/TrEMBL
      H0VLN2

    4. XM_013149668.3 → XP_013005122.1  histone-lysine N-methyltransferase EZH1

      See identical proteins and their annotated locations for XP_013005122.1

      UniProtKB/TrEMBL
      H0VLN2
      Related
      ENSCPOP00000011277.2
      Conserved Domains (5) summary
      smart00717
      Location:433 → 474
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      smart00317
      Location:613 → 734
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG2940
      Location:463 → 727
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      cd00167
      Location:433 → 474
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam11616
      Location:39 → 67
      EZH2_WD-Binding; WD repeat binding protein EZH2

    5. XM_063251606.1 → XP_063107676.1  histone-lysine N-methyltransferase EZH1

      UniProtKB/TrEMBL
      H0VLN2
    Nucleotide Protein
    Heading Accession and Version

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