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    Mettl1 methyltransferase 1, tRNA methylguanosine [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100714146, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Mettl1
    Gene description
    methyltransferase 1, tRNA methylguanosine
    See related
    Ensembl:ENSCPOG00000000066
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Mettl1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947491.1 (51176289..51179542, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176410.1 (40052711..40056326)

    NW_026947491.1Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 9 Neighboring gene 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Neighboring gene EEF1A lysine methyltransferase 3 Neighboring gene Ts translation elongation factor, mitochondrial Neighboring gene advillin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tRNA (guanine(46)-N7)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA (guanine-N7)-methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of tRNA methyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA (guanine-N(7)-)-methyltransferase
    Names
    methyltransferase like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947491.1 Reference mCavPor4.1

      Range
      51176289..51179542 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023560009.2 → XP_023415777.1  tRNA (guanine-N(7)-)-methyltransferase isoform X2

      UniProtKB/TrEMBL
      H0UT38
      Conserved Domains (1) summary
      cl17173
      Location:101 → 244
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. XM_005008534.3 → XP_005008591.2  tRNA (guanine-N(7)-)-methyltransferase isoform X1

      UniProtKB/TrEMBL
      H0UT38
      Related
      ENSCPOP00000000058.3
      Conserved Domains (2) summary
      COG0220
      Location:40 → 282
      TrmB; tRNA G46 methylase TrmB [Translation, ribosomal structure and biogenesis]
      pfam02390
      Location:101 → 278
      Methyltransf_4; Putative methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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