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    PTGER4 prostaglandin E receptor 4 [ Sus scrofa (pig) ]

    Gene ID: 100625072, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PTGER4provided by VGNC
    Official Full Name
    prostaglandin E receptor 4provided by VGNC
    Primary source
    VGNC:VGNC:91949
    See related
    Ensembl:ENSSSCG00000024439
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in spleen (RPKM 10.6), kidney (RPKM 4.5) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See PTGER4 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 16 NC_010458.4 (25670832..25686556)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003541347.2 (48181..62549)

    Chromosome 16 - NC_010458.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106506472 Neighboring gene uncharacterized LOC106506475 Neighboring gene DNA endonuclease RBBP8 pseudogene Neighboring gene tetratricopeptide repeat domain 33

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables prostaglandin E receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to prostaglandin E stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prostaglandin E2 receptor EP4 subtype

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010458.4 Reference Sscrofa11.1 Primary Assembly

      Range
      25670832..25686556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021076655.1 → XP_020932314.1  prostaglandin E2 receptor EP4 subtype

      UniProtKB/TrEMBL
      A0A0B8RTB7, A0A4X1T156, A0A8D0JFT9, I3LLK4
      Related
      ENSSSCP00000024974.2, ENSSSCT00000030022.3
      Conserved Domains (1) summary
      cd15142
      Location:19 → 345
      7tmA_PGE2_EP4; prostaglandin E2 receptor EP4 subtype, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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