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    SIAH2 siah E3 ubiquitin protein ligase 2 [ Sus scrofa (pig) ]

    Gene ID: 100622531, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SIAH2provided by VGNC
    Official Full Name
    siah E3 ubiquitin protein ligase 2provided by VGNC
    Primary source
    VGNC:VGNC:92866
    See related
    Ensembl:ENSSSCG00000031388
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in heart (RPKM 22.8), kidney (RPKM 10.4) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See SIAH2 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (90951798..90971538, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (99076306..99096119, complement)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S23 pseudogene Neighboring gene selenoprotein T Neighboring gene glutamate rich 6 Neighboring gene uncharacterized LOC110256317 Neighboring gene uncharacterized LOC110255174 Neighboring gene uncharacterized LOC110256316 Neighboring gene clarin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase SIAH2
    Names
    seven in absentia homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      90951798..90971538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003358611.4 → XP_003358659.1  E3 ubiquitin-protein ligase SIAH2

      UniProtKB/TrEMBL
      A0A287ASV6, A0A4X1SW38
      Related
      ENSSSCP00000046937.1, ENSSSCT00000036924.2
      Conserved Domains (1) summary
      pfam03145
      Location:122 → 318
      Sina; Seven in absentia protein family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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