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    TNNI3K TNNI3 interacting kinase [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100533992, updated on 10-Oct-2024

    Summary

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    Gene symbol
    TNNI3K
    Gene description
    TNNI3 interacting kinase
    See related
    Ensembl:ENSOCUG00000003001
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See TNNI3K in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 13 NC_067386.1 (91332157..91691189, complement)

    Chromosome 13 - NC_067386.1Genomic Context describing neighboring genes Neighboring gene crystallin zeta Neighboring gene glutamate rich 3 Neighboring gene leucine rich repeat containing 53 Neighboring gene uncharacterized LOC127493437 Neighboring gene leucine rich repeats and IQ motif containing 3 Neighboring gene fucose-1-phosphate guanylyltransferase Neighboring gene ADP/ATP translocase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067386.1 Chromosome 13 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II-specific DNA-binding transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein localization to ciliary inversin compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ciliary inversin compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase TNNI3K
    NP_001191736.1
    XP_002715966.1
    XP_017201017.1
    XP_017201018.1
    XP_017201020.1
    XP_017201023.1
    XP_017201024.1
    XP_051712081.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204807.2 → NP_001191736.1  serine/threonine-protein kinase TNNI3K

      See identical proteins and their annotated locations for NP_001191736.1

      Status: PROVISIONAL

      Source sequence(s)
      VIYN02003002
      UniProtKB/TrEMBL
      A0A5F9D5W6, G1SIU1
      Conserved Domains (6) summary
      cd00204
      Location:99 → 220
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd14064
      Location:469 → 722
      PKc_TNNI3K; Catalytic domain of the Dual-specificity protein kinase, TNNI3-interacting kinase
      pfam07714
      Location:463 → 719
      Pkinase_Tyr; Protein tyrosine kinase
      pfam12796
      Location:105 → 195
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:200 → 255
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:134 → 164
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067386.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      91332157..91691189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017345534.2 → XP_017201023.1  serine/threonine-protein kinase TNNI3K isoform X6

      UniProtKB/TrEMBL
      A0A5F9CK64, A0A5F9D5W6
      Related
      ENSOCUP00000034086.1

    2. XM_002715920.4 → XP_002715966.1  serine/threonine-protein kinase TNNI3K isoform X4

      See identical proteins and their annotated locations for XP_002715966.1

      UniProtKB/TrEMBL
      A0A5F9D5W6, G1SIU1
      Related
      ENSOCUP00000002612.4
      Conserved Domains (6) summary
      cd00204
      Location:99 → 220
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd14064
      Location:469 → 722
      PKc_TNNI3K; Catalytic domain of the Dual-specificity protein kinase, TNNI3-interacting kinase
      pfam07714
      Location:463 → 719
      Pkinase_Tyr; Protein tyrosine kinase
      pfam12796
      Location:105 → 195
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:200 → 255
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:134 → 164
      ANK; ANK repeat [structural motif]

    3. XM_051856121.1 → XP_051712081.1  serine/threonine-protein kinase TNNI3K isoform X2

    4. XM_017345531.2 → XP_017201020.1  serine/threonine-protein kinase TNNI3K isoform X5

      UniProtKB/TrEMBL
      A0A5F9D5W6

    5. XM_017345529.2 → XP_017201018.1  serine/threonine-protein kinase TNNI3K isoform X3

      UniProtKB/TrEMBL
      A0A5F9D5W6

    6. XM_017345528.2 → XP_017201017.1  serine/threonine-protein kinase TNNI3K isoform X1

      UniProtKB/TrEMBL
      A0A5F9D5W6

    7. XM_017345535.2 → XP_017201024.1  serine/threonine-protein kinase TNNI3K isoform X7

      UniProtKB/TrEMBL
      A0A5F9D5W6
    Nucleotide Protein
    Heading Accession and Version

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