MIR155 microRNA mir-155 [Sus scrofa (pig)] - Gene

Summary

Gene symbol: MIR155
Gene description: microRNA mir-155
See related: Ensembl:ENSSSCG00000019154 miRBase:MI0015907
Gene type: ncRNA
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: ssc-mir-155
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

Location:: chromosome: 13

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	13	NC_010455.5 (189138822..189138902)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	13	NC_010455.4 (199063344..199063424, complement)

Chromosome 13 - NC_010455.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

miR-155-5p improves oocyte maturation in porcine cumulus cells through connexin 43-mediated regulation of MPF activity.
Title: miR-155-5p improves oocyte maturation in porcine cumulus cells through connexin 43-mediated regulation of MPF activity.
Influences of miR-155/NF-kappaB signaling pathway on inflammatory factors in ARDS in neonatal pigs.
Title: Influences of miR-155/NF-κB signaling pathway on inflammatory factors in ARDS in neonatal pigs.
Identification of mutations at FOXP3 binding site within BIC gene that result in increased expression of miR-155 in pig.
Title: Identification of functional mutations at FOXP3 binding site within BIC gene that alter the expression of miR-155 in pigs.
this study offers new evidence on the immune function of miR-155 in pigs.
Title: Molecular characterisation of porcine miR-155 and its regulatory roles in the TLR3/TLR4 pathways.
Research indicated that OLFML3 gene may affect prenatal skeletal muscle development and was regulated by miR-155.
Title: OLFML3 expression is decreased during prenatal muscle development and regulated by microRNA-155 in pigs.

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General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.