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    SGPL1 sphingosine-1-phosphate lyase 1 [ Sus scrofa (pig) ]

    Gene ID: 100525187, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SGPL1provided by VGNC
    Official Full Name
    sphingosine-1-phosphate lyase 1provided by VGNC
    Primary source
    VGNC:VGNC:92797
    See related
    Ensembl:ENSSSCG00000010274
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in ovary (RPKM 17.7), spleen (RPKM 15.9) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See SGPL1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (73696902..73781830)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (79572301..79628480)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 14 Neighboring gene 60 kDa heat shock protein, mitochondrial pseudogene Neighboring gene thymus, brain and testes associated Neighboring gene pterin-4 alpha-carbinolamine dehydratase 1 Neighboring gene uncharacterized LOC110256788 Neighboring gene uncharacterized LOC110256673 Neighboring gene uncharacterized LOC110256672

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sphinganine-1-phosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carboxylic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingolipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingosine-1-phosphate lyase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      73696902..73781830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005657411.3 → XP_005657468.1  sphingosine-1-phosphate lyase 1 isoform X4

      See identical proteins and their annotated locations for XP_005657468.1

      UniProtKB/TrEMBL
      A0A8D0NBX6, A0A8D0TKS3, A0A8D1ZUH1, K9IVV1
      Conserved Domains (1) summary
      cd06450
      Location:146 → 507
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    2. XM_003133063.4 → XP_003133111.1  sphingosine-1-phosphate lyase 1 isoform X4

      See identical proteins and their annotated locations for XP_003133111.1

      UniProtKB/TrEMBL
      A0A8D0NBX6, A0A8D0TKS3, A0A8D1ZUH1, K9IVV1
      Related
      ENSSSCP00000046783.2, ENSSSCT00000056069.3
      Conserved Domains (1) summary
      cd06450
      Location:146 → 507
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    3. XM_005657406.3 → XP_005657463.1  sphingosine-1-phosphate lyase 1 isoform X1

      UniProtKB/TrEMBL
      A0A287BGV0, A0A8D1PLX7
      Related
      ENSSSCP00000054654.2, ENSSSCT00000045496.3
      Conserved Domains (1) summary
      cd06450
      Location:179 → 540
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    4. XM_005657410.3 → XP_005657467.1  sphingosine-1-phosphate lyase 1 isoform X4

      See identical proteins and their annotated locations for XP_005657467.1

      UniProtKB/TrEMBL
      A0A8D0NBX6, A0A8D0TKS3, A0A8D1ZUH1, K9IVV1
      Conserved Domains (1) summary
      cd06450
      Location:146 → 507
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    5. XM_005657409.3 → XP_005657466.1  sphingosine-1-phosphate lyase 1 isoform X4

      See identical proteins and their annotated locations for XP_005657466.1

      UniProtKB/TrEMBL
      A0A8D0NBX6, A0A8D0TKS3, A0A8D1ZUH1, K9IVV1
      Related
      ENSSSCP00000047377.2, ENSSSCT00000047829.2
      Conserved Domains (1) summary
      cd06450
      Location:146 → 507
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    6. XM_005657407.3 → XP_005657464.1  sphingosine-1-phosphate lyase 1 isoform X2

      UniProtKB/TrEMBL
      A0A287AX55, A0A4X1TEJ6, A0A8D0NA08, A0A8D0Y1S1
      Related
      ENSSSCP00000048727.2, ENSSSCT00000064467.3
      Conserved Domains (1) summary
      cd06450
      Location:175 → 536
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    7. XM_005657408.3 → XP_005657465.1  sphingosine-1-phosphate lyase 1 isoform X3

      UniProtKB/TrEMBL
      A0A4X1TEJ6, A0A8D0NA08
      Related
      ENSSSCP00000055280.2, ENSSSCT00000042658.2
      Conserved Domains (1) summary
      cd06450
      Location:173 → 534
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    8. XM_021073925.1 → XP_020929584.1  sphingosine-1-phosphate lyase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8D0NBX6, A0A8D0TKS3, A0A8D1ZUH1, K9IVV1
      Conserved Domains (1) summary
      cd06450
      Location:146 → 507
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

    RNA

    1. XR_002338876.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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