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    KPNB1 karyopherin subunit beta 1 [ Sus scrofa (pig) ]

    Gene ID: 100518449, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KPNB1provided by VGNC
    Official Full Name
    karyopherin subunit beta 1provided by VGNC
    Primary source
    VGNC:VGNC:89567
    See related
    Ensembl:ENSSSCG00000017514
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in spleen (RPKM 45.9), lung (RPKM 34.3) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See KPNB1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (23915783..23945407)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (23785821..23813399)

    Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L45 Neighboring gene aminopeptidase puromycin sensitive Neighboring gene TBK1 binding protein 1 Neighboring gene uncharacterized LOC110255911

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin subunit beta-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

      Range
      23915783..23945407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003131528.6 → XP_003131576.3  importin subunit beta-1

      See identical proteins and their annotated locations for XP_003131576.3

      UniProtKB/TrEMBL
      A0A8D0WQ49, A0A8D0ZHD7, F1RWJ5, K9IVR9
      Related
      ENSSSCP00000018562.3, ENSSSCT00000019068.5
      Conserved Domains (4) summary
      COG5215
      Location:2 → 871
      KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
      cd00020
      Location:365 → 479
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam03810
      Location:21 → 101
      IBN_N; Importin-beta N-terminal domain
      sd00044
      Location:323 → 354
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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