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    WLS Wnt ligand secretion mediator [ Sus scrofa (pig) ]

    Gene ID: 100516916, updated on 17-Aug-2024

    Summary

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    Official Symbol
    WLSprovided by VGNC
    Official Full Name
    Wnt ligand secretion mediatorprovided by VGNC
    Primary source
    VGNC:VGNC:94961
    See related
    Ensembl:ENSSSCG00000003795
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    GPR177
    Expression
    Broad expression in kidney (RPKM 32.7), ovary (RPKM 26.6) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See WLS in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (144242639..144529659)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (133711371..133819072)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene DEP domain containing 1 Neighboring gene uncharacterized LOC106509878 Neighboring gene retinoid isomerohydrolase RPE65 Neighboring gene uncharacterized LOC110261211 Neighboring gene DIRAS family GTPase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Wnt-protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Wnt protein secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in organelle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein wntless homolog
    Names
    G protein-coupled receptor 177
    wntless Wnt ligand secretion mediator
    wntless homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      144242639..144529659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021096488.1 → XP_020952147.1  protein wntless homolog isoform X2

      UniProtKB/TrEMBL
      A0A287A5R0, A0A4X1U477, A0A8D0VQU9, A0A8D1AT34
      Conserved Domains (1) summary
      pfam06664
      Location:133 → 451
      MIG-14_Wnt-bd; Wnt-binding factor required for Wnt secretion

    2. XM_003482073.4 → XP_003482121.1  protein wntless homolog isoform X1

      See identical proteins and their annotated locations for XP_003482121.1

      UniProtKB/TrEMBL
      A0A0B8RT00, A0A4X1U8B3, A0A5G2QGA6, A0A8D0VTI6, A0A8D1RR03
      Related
      ENSSSCP00000063787.1, ENSSSCT00000080486.1
      Conserved Domains (1) summary
      pfam06664
      Location:178 → 496
      MIG-14_Wnt-bd; Wnt-binding factor required for Wnt secretion

    3. XM_021096489.1 → XP_020952148.1  protein wntless homolog isoform X2

      UniProtKB/TrEMBL
      A0A287A5R0, A0A4X1U477, A0A8D0VQU9, A0A8D1AT34
      Related
      ENSSSCP00000039148.1, ENSSSCT00000050984.3
      Conserved Domains (1) summary
      pfam06664
      Location:133 → 451
      MIG-14_Wnt-bd; Wnt-binding factor required for Wnt secretion
    Nucleotide Protein Strain
    Heading Accession and Version

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