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    MARS1 methionyl-tRNA synthetase 1 [ Sus scrofa (pig) ]

    Gene ID: 100516610, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MARS1provided by VGNC
    Official Full Name
    methionyl-tRNA synthetase 1provided by VGNC
    Primary source
    VGNC:VGNC:90028
    See related
    Ensembl:ENSSSCG00000023318
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    MARS
    Expression
    Ubiquitous expression in ovary (RPKM 24.2), spleen (RPKM 18.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See MARS1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (22752405..22785509)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003613507.1 (120993..139964, complement)

    Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene inhibin subunit beta E Neighboring gene GLI family zinc finger 1 Neighboring gene Rho GTPase activating protein 9 Neighboring gene DNA damage inducible transcript 3 Neighboring gene methyl-CpG binding domain protein 6 Neighboring gene dynactin subunit 2 Neighboring gene kinesin family member 5A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables methionine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methionyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of aminoacyl-tRNA synthetase multienzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methionine--tRNA ligase, cytoplasmic

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

      Range
      22752405..22785509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021091866.1 → XP_020947525.1  methionine--tRNA ligase, cytoplasmic isoform X1

      UniProtKB/TrEMBL
      A0A4X1W5F1, I3LCC2
      Related
      ENSSSCP00000021697.2, ENSSSCT00000031280.4
      Conserved Domains (4) summary
      cd10307
      Location:126 → 228
      GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
      cd00939
      Location:902 → 946
      MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
      cl00388
      Location:50 → 117
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
      cl26127
      Location:300 → 886
      PRK12267; methionyl-tRNA synthetase; Reviewed

    2. XM_021091867.1 → XP_020947526.1  methionine--tRNA ligase, cytoplasmic isoform X2

      UniProtKB/TrEMBL
      A0A4X1W7P6, I3LA63
      Related
      ENSSSCP00000020929.2, ENSSSCT00000028772.4
      Conserved Domains (3) summary
      cd10307
      Location:126 → 228
      GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
      cl00388
      Location:50 → 117
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
      cl26127
      Location:300 → 925
      PRK12267; methionyl-tRNA synthetase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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