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    CNP 2',3'-cyclic nucleotide 3' phosphodiesterase [ Sus scrofa (pig) ]

    Gene ID: 100511587, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CNPprovided by VGNC
    Official Full Name
    2',3'-cyclic nucleotide 3' phosphodiesteraseprovided by VGNC
    Primary source
    VGNC:VGNC:86840
    See related
    Ensembl:ENSSSCG00000017420
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in spleen (RPKM 44.1), mixtures (RPKM 41.7) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See CNP in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (20758081..20765655, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (21048293..21055830, complement)

    Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene zinc finger protein 385C Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene outer dynein arm docking complex subunit 4 Neighboring gene ATP citrate lyase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cyclic nucleotide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2',3'-cyclic-nucleotide 3'-phosphodiesterase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

      Range
      20758081..20765655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003131420.5 → XP_003131468.2  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1

      UniProtKB/TrEMBL
      A0A480ZVP3, A0A4X1U6Z9, A0A4X1U7L2, A0A8D1NMX7
      Related
      ENSSSCP00000048981.2, ENSSSCT00000059642.3
      Conserved Domains (3) summary
      pfam05881
      Location:186 → 398
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      pfam13671
      Location:52 → 165
      AAA_33; AAA domain
      cl17190
      Location:51 → 176
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. XM_021066991.1 → XP_020922650.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X2

      UniProtKB/TrEMBL
      A0A480XA27, A0A4X1U2F5, A0A8D0J627
      Conserved Domains (2) summary
      pfam05881
      Location:166 → 378
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      cl26098
      Location:32 → 145
      AAA_33; AAA domain

    3. XM_021066992.1 → XP_020922651.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X2

      UniProtKB/TrEMBL
      A0A480XA27, A0A4X1U2F5, A0A8D0J627
      Related
      ENSSSCP00000040638.3, ENSSSCT00000049227.3
      Conserved Domains (2) summary
      pfam05881
      Location:166 → 378
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      cl26098
      Location:32 → 145
      AAA_33; AAA domain
    Nucleotide Protein
    Heading Accession and Version

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