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    Gcc1 GRIP and coiled-coil domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361513, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Gcc1provided by RGD
    Official Full Name
    GRIP and coiled-coil domain containing 1provided by RGD
    Primary source
    RGD:2319954
    See related
    EnsemblRapid:ENSRNOG00000007792 AllianceGenome:RGD:2319954
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human GCC1 (GRIP and coiled-coil domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 34.9), Kidney (RPKM 34.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gcc1 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (57996261..58008126, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (57030817..57042682, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (55708040..55719884, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 800 Neighboring gene H3 histone, family 3C like 2 Neighboring gene U1 spliceosomal RNA Neighboring gene ADP-ribosylation factor 5 Neighboring gene fascin actin-bundling protein 3 Neighboring gene uncharacterized LOC134486564 Neighboring gene paired box 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GRIP and coiled-coil domain-containing protein 1
    Names
    rCG28300-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427123.1 → NP_001414052.1  GRIP and coiled-coil domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6IEA5, D3ZPA1
      Related
      ENSRNOP00000010246.4, ENSRNOT00000010246.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      57996261..58008126 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236235.5 → XP_006236297.1  GRIP and coiled-coil domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006236297.1

      UniProtKB/TrEMBL
      A6IEA5, D3ZPA1
      Conserved Domains (2) summary
      PRK03918
      Location:153 → 608
      PRK03918; DNA double-strand break repair ATPase Rad50
      pfam01465
      Location:721 → 763
      GRIP; GRIP domain

    2. XM_039108620.2 → XP_038964548.1  GRIP and coiled-coil domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A6IEA5, D3ZPA1
      Conserved Domains (2) summary
      PRK03918
      Location:153 → 608
      PRK03918; DNA double-strand break repair ATPase Rad50
      pfam01465
      Location:721 → 763
      GRIP; GRIP domain

    3. XM_006236234.5 → XP_006236296.1  GRIP and coiled-coil domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006236296.1

      UniProtKB/TrEMBL
      A6IEA5, D3ZPA1
      Conserved Domains (2) summary
      PRK03918
      Location:153 → 608
      PRK03918; DNA double-strand break repair ATPase Rad50
      pfam01465
      Location:721 → 763
      GRIP; GRIP domain
    Nucleotide Protein Strain
    Heading Accession and Version

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