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    TFR2 transferrin receptor 2 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100357314, updated on 8-Mar-2024

    Summary

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    Gene symbol
    TFR2
    Gene description
    transferrin receptor 2
    See related
    Ensembl:ENSOCUG00000016902
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See TFR2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 6 NC_067379.1 (27149651..27160380)

    Chromosome 6 - NC_067379.1Genomic Context describing neighboring genes Neighboring gene G protein subunit beta 2 Neighboring gene actin like 6B Neighboring gene uncharacterized LOC103348618 Neighboring gene uncharacterized LOC108176796 Neighboring gene motile sperm domain containing 3 Neighboring gene procollagen C-endopeptidase enhancer

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067379.1 Chromosome 6 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transferrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endocytic iron import into cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transferrin transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transferrin receptor protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067379.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      27149651..27160380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008257995.3 → XP_008256217.1  transferrin receptor protein 2 isoform X3

      UniProtKB/TrEMBL
      G1TTY5
      Related
      ENSOCUP00000020508.2
      Conserved Domains (3) summary
      cd09848
      Location:400 → 633
      M28_TfR; M28 Zn-peptidase Transferrin Receptor family
      cd02128
      Location:202 → 387
      PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
      pfam04253
      Location:665 → 778
      TFR_dimer; Transferrin receptor-like dimerization domain

    2. XM_051847702.1 → XP_051703662.1  transferrin receptor protein 2 isoform X2

    3. XM_002711913.4 → XP_002711959.1  transferrin receptor protein 2 isoform X1

      UniProtKB/TrEMBL
      G1TTY5
      Conserved Domains (3) summary
      cd09848
      Location:409 → 642
      M28_TfR; M28 Zn-peptidase Transferrin Receptor family
      cd02128
      Location:211 → 396
      PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
      pfam04253
      Location:674 → 787
      TFR_dimer; Transferrin receptor-like dimerization domain
    Nucleotide Protein
    Heading Accession and Version

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