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    GRIK2 glutamate ionotropic receptor kainate type subunit 2 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100356816, updated on 10-Oct-2024

    Summary

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    Gene symbol
    GRIK2
    Gene description
    glutamate ionotropic receptor kainate type subunit 2
    See related
    Ensembl:ENSOCUG00000003845
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See GRIK2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 12 NC_067385.1 (65873586..66608923, complement)

    Chromosome 12 - NC_067385.1Genomic Context describing neighboring genes Neighboring gene actin-related protein 2/3 complex subunit 5-like protein Neighboring gene dihydroxyacetone phosphate acyltransferase-like Neighboring gene small nuclear ribonucleoprotein-associated protein B-like Neighboring gene ATP synthase F(0) complex subunit B1, mitochondrial-like Neighboring gene uncharacterized LOC127493332 Neighboring gene uncharacterized LOC127493172 Neighboring gene insulin-like growth factor-binding protein 3 receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067385.1 Chromosome 12 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kainate selective glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of kainate selective glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor ionotropic, kainate 2
    Names
    glutamate receptor, ionotropic, kainate 2
    glutamate receptor, ionotropic, kainate 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067385.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      65873586..66608923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002714794.4 → XP_002714840.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F9DNI8, G1SKJ0
      Related
      ENSOCUP00000003334.3
      Conserved Domains (4) summary
      pfam00060
      Location:562 → 831
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:52 → 395
      ANF_receptor; Receptor family ligand binding region
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    2. XM_017345301.2 → XP_017200790.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F9DNI8, G1SKJ0
      Conserved Domains (4) summary
      pfam00060
      Location:562 → 831
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:52 → 395
      ANF_receptor; Receptor family ligand binding region
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    3. XM_051855434.1 → XP_051711394.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      G1SKJ0

    4. XM_051855437.1 → XP_051711397.1  glutamate receptor ionotropic, kainate 2 isoform X4

    5. XM_008263318.3 → XP_008261540.1  glutamate receptor ionotropic, kainate 2 isoform X3

      See identical proteins and their annotated locations for XP_008261540.1

      UniProtKB/TrEMBL
      A0A5F9DNI8, U3KM52
      Related
      ENSOCUP00000026310.2
      Conserved Domains (4) summary
      pfam00060
      Location:562 → 831
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:52 → 395
      ANF_receptor; Receptor family ligand binding region
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    6. XM_051855435.1 → XP_051711395.1  glutamate receptor ionotropic, kainate 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F9CX88

    7. XM_051855436.1 → XP_051711396.1  glutamate receptor ionotropic, kainate 2 isoform X3

      UniProtKB/TrEMBL
      U3KM52

    8. XM_051855439.1 → XP_051711399.1  glutamate receptor ionotropic, kainate 2 isoform X5

    Nucleotide Protein
    Heading Accession and Version

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