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    KCNH8 potassium voltage-gated channel subfamily H member 8 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100349166, updated on 8-Mar-2024

    Summary

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    Gene symbol
    KCNH8
    Gene description
    potassium voltage-gated channel subfamily H member 8
    See related
    Ensembl:ENSOCUG00000016348
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See KCNH8 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 14 NC_067387.1 (6393227..6845407)

    Chromosome 14 - NC_067387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103350357 Neighboring gene 60S ribosomal protein L17-like Neighboring gene cytokine-like nuclear factor N-PAC Neighboring gene uncharacterized LOC127483113 Neighboring gene uncharacterized LOC127493913

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067387.1 Chromosome 14 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    potassium voltage-gated channel subfamily H member 8
    Names
    potassium voltage-gated channel, subfamily H (eag-related), member 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067387.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      6393227..6845407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002716200.4 → XP_002716246.1  potassium voltage-gated channel subfamily H member 8

      UniProtKB/TrEMBL
      G1TBG1
      Related
      ENSOCUP00000014056.2
      Conserved Domains (6) summary
      COG0664
      Location:548 → 685
      Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
      cd00038
      Location:551 → 662
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00130
      Location:42 → 133
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
      pfam00520
      Location:239 → 481
      Ion_trans; Ion transport protein
      pfam07885
      Location:421 → 475
      Ion_trans_2; Ion channel
      pfam13426
      Location:29 → 135
      PAS_9; PAS domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials