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    PBRM1 polybromo 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100347818, updated on 10-Oct-2024

    Summary

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    Gene symbol
    PBRM1
    Gene description
    polybromo 1
    See related
    Ensembl:ENSOCUG00000009829
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See PBRM1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 9 NC_067382.1 (96354975..96488718)

    Chromosome 9 - NC_067382.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD19B Neighboring gene small nucleolar RNA SNORD19 Neighboring gene G protein nucleolar 3 Neighboring gene small integral membrane protein 4 Neighboring gene 5'-nucleotidase domain containing 2 Neighboring gene stabilin 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067382.1 Chromosome 9 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RSC-type complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein polybromo-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067382.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      96354975..96488718
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051851540.1 → XP_051707500.1  protein polybromo-1 isoform X1

    2. XM_051851558.1 → XP_051707518.1  protein polybromo-1 isoform X14

    3. XM_051851544.1 → XP_051707504.1  protein polybromo-1 isoform X3

    4. XM_051851548.1 → XP_051707508.1  protein polybromo-1 isoform X6

    5. XM_051851549.1 → XP_051707509.1  protein polybromo-1 isoform X7

    6. XM_051851543.1 → XP_051707503.1  protein polybromo-1 isoform X2

    7. XM_051851546.1 → XP_051707506.1  protein polybromo-1 isoform X4

    8. XM_051851547.1 → XP_051707507.1  protein polybromo-1 isoform X5

    9. XM_051851551.1 → XP_051707511.1  protein polybromo-1 isoform X9

    10. XM_051851552.1 → XP_051707512.1  protein polybromo-1 isoform X9

    11. XM_051851559.1 → XP_051707519.1  protein polybromo-1 isoform X15

    12. XM_051851568.1 → XP_051707528.1  protein polybromo-1 isoform X26

    13. XM_008260774.3 → XP_008258996.1  protein polybromo-1 isoform X10

      See identical proteins and their annotated locations for XP_008258996.1

      UniProtKB/TrEMBL
      G1SY04
      Conserved Domains (9) summary
      cd05515
      Location:694 → 798
      Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05517
      Location:203 → 305
      Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05518
      Location:555 → 658
      Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05520
      Location:404 → 505
      Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05524
      Location:65 → 176
      Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05526
      Location:811 → 918
      Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd00084
      Location:1416 → 1480
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cd04717
      Location:993 → 1110
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
      pfam08226
      Location:1480 → 1534
      DUF1720; Domain of unknown function (DUF1720)

    14. XM_051851556.1 → XP_051707516.1  protein polybromo-1 isoform X11

    15. XM_051851557.1 → XP_051707517.1  protein polybromo-1 isoform X13

    16. XM_051851550.1 → XP_051707510.1  protein polybromo-1 isoform X8

    17. XM_017343873.2 → XP_017199362.1  protein polybromo-1 isoform X16

      UniProtKB/TrEMBL
      A0A5F9DCQ1

    18. XM_008260782.3 → XP_008259004.1  protein polybromo-1 isoform X17

      UniProtKB/TrEMBL
      A0A5F9CXV8
      Conserved Domains (8) summary
      cd05515
      Location:694 → 798
      Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05517
      Location:203 → 305
      Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05518
      Location:555 → 658
      Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05520
      Location:404 → 505
      Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05524
      Location:65 → 176
      Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05526
      Location:811 → 918
      Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd00084
      Location:1416 → 1465
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cd04717
      Location:993 → 1110
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

    19. XM_008260786.3 → XP_008259008.1  protein polybromo-1 isoform X28

      UniProtKB/TrEMBL
      A0A5F9C1B8
      Conserved Domains (8) summary
      cd05515
      Location:694 → 798
      Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05517
      Location:203 → 305
      Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05518
      Location:555 → 658
      Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05520
      Location:404 → 505
      Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05524
      Location:65 → 176
      Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05526
      Location:811 → 918
      Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd00084
      Location:1416 → 1465
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cd04717
      Location:993 → 1110
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

    20. XM_051851571.1 → XP_051707531.1  protein polybromo-1 isoform X29

    21. XM_008260780.3 → XP_008259002.1  protein polybromo-1 isoform X12

      UniProtKB/TrEMBL
      G1SY04
      Conserved Domains (9) summary
      cd05515
      Location:679 → 783
      Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05517
      Location:203 → 305
      Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05518
      Location:540 → 643
      Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05520
      Location:404 → 505
      Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05524
      Location:65 → 176
      Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05526
      Location:796 → 903
      Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd00084
      Location:1401 → 1465
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cd04717
      Location:978 → 1095
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
      pfam08226
      Location:1465 → 1519
      DUF1720; Domain of unknown function (DUF1720)

    22. XM_051851562.1 → XP_051707522.1  protein polybromo-1 isoform X20

    23. XM_008260783.3 → XP_008259005.1  protein polybromo-1 isoform X22

      UniProtKB/TrEMBL
      A0A5F9CXV8
      Conserved Domains (8) summary
      cd05515
      Location:679 → 783
      Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05517
      Location:203 → 305
      Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05518
      Location:540 → 643
      Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05520
      Location:404 → 505
      Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05524
      Location:65 → 176
      Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05526
      Location:796 → 903
      Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd00084
      Location:1401 → 1450
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cd04717
      Location:978 → 1095
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

    24. XM_051851564.1 → XP_051707524.1  protein polybromo-1 isoform X21

    25. XM_051851565.1 → XP_051707525.1  protein polybromo-1 isoform X23

    26. XM_051851574.1 → XP_051707534.1  protein polybromo-1 isoform X32

    27. XM_051851560.1 → XP_051707520.1  protein polybromo-1 isoform X18

    28. XM_051851561.1 → XP_051707521.1  protein polybromo-1 isoform X19

    29. XM_051851573.1 → XP_051707533.1  protein polybromo-1 isoform X30

    30. XM_051851566.1 → XP_051707526.1  protein polybromo-1 isoform X24

    31. XM_051851567.1 → XP_051707527.1  protein polybromo-1 isoform X25

    32. XM_002713243.4 → XP_002713289.2  protein polybromo-1 isoform X31

      UniProtKB/TrEMBL
      A0A5F9C1B8
      Related
      ENSOCUP00000027459.1
      Conserved Domains (8) summary
      cd05515
      Location:679 → 783
      Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05517
      Location:203 → 305
      Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05518
      Location:540 → 643
      Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05520
      Location:404 → 505
      Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05524
      Location:65 → 176
      Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd05526
      Location:796 → 903
      Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
      cd00084
      Location:1401 → 1450
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cd04717
      Location:978 → 1095
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

    33. XM_051851575.1 → XP_051707535.1  protein polybromo-1 isoform X33

    34. XM_051851576.1 → XP_051707536.1  protein polybromo-1 isoform X34

    35. XM_051851542.1 → XP_051707502.1  protein polybromo-1 isoform X1

    36. XM_051851554.1 → XP_051707514.1  protein polybromo-1 isoform X9

    37. XM_051851553.1 → XP_051707513.1  protein polybromo-1 isoform X9

    38. XM_051851541.1 → XP_051707501.1  protein polybromo-1 isoform X1

    39. XM_051851570.1 → XP_051707530.1  protein polybromo-1 isoform X27

    40. XM_051851569.1 → XP_051707529.1  protein polybromo-1 isoform X27

    Nucleotide Protein
    Heading Accession and Version

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