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    DBT dihydrolipoamide branched chain transacylase E2 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100346987, updated on 8-Mar-2024

    Summary

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    Gene symbol
    DBT
    Gene description
    dihydrolipoamide branched chain transacylase E2
    See related
    Ensembl:ENSOCUG00000014244
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See DBT in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 13 NC_067386.1 (64125177..64172640)

    Chromosome 13 - NC_067386.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 14A Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene matrin 3 pseudogene Neighboring gene leucine rich repeat containing 39 Neighboring gene tRNA methyltransferase 13 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067386.1 Chromosome 13 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipoic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067386.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      64125177..64172640
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002715835.4 → XP_002715881.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A5F9CX38, G1T701
      Related
      ENSOCUP00000012242.2
      Conserved Domains (4) summary
      cd06849
      Location:65 → 138
      lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
      PLN02528
      Location:67 → 482
      PLN02528; 2-oxoisovalerate dehydrogenase E2 component
      pfam00198
      Location:267 → 479
      2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
      pfam02817
      Location:172 → 205
      E3_binding; e3 binding domain

    2. XM_051857453.1 → XP_051713413.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X2

    3. XM_051857454.1 → XP_051713414.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X2

    Nucleotide Protein
    Heading Accession and Version

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