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    KPNA5 karyopherin subunit alpha 5 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100343572, updated on 10-Oct-2024

    Summary

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    Gene symbol
    KPNA5
    Gene description
    karyopherin subunit alpha 5
    See related
    Ensembl:ENSOCUG00000007812
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human all
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    Genomic context

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    See KPNA5 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 12 NC_067385.1 (50205778..50301200, complement)

    Chromosome 12 - NC_067385.1Genomic Context describing neighboring genes Neighboring gene cysteine-rich protein 2-like Neighboring gene G protein-coupled receptor class C group 6 member A Neighboring gene small nucleolar RNA SNORD73 Neighboring gene family with sequence similarity 162 member B Neighboring gene zinc finger CCHC-type and RNA-binding motif-containing protein 1-like Neighboring gene zinc finger containing ubiquitin peptidase 1 Neighboring gene radial spoke head component 4A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067385.1 Chromosome 12 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin subunit alpha-6
    Names
    karyopherin alpha 5 (importin alpha 6)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067385.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      50205778..50301200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051855390.1 → XP_051711350.1  importin subunit alpha-6 isoform X3

    2. XM_008263417.3 → XP_008261639.1  importin subunit alpha-6 isoform X4

      UniProtKB/TrEMBL
      A0A5F9C7G6
      Related
      ENSOCUP00000029792.1
      Conserved Domains (3) summary
      cd00020
      Location:254 → 368
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:9 → 105
      IBB; Importin beta binding domain
      sd00043
      Location:334 → 366
      ARM; armadillo repeat [structural motif]

    3. XM_051855389.1 → XP_051711349.1  importin subunit alpha-6 isoform X2

    4. XM_002714763.4 → XP_002714809.2  importin subunit alpha-6 isoform X1

      UniProtKB/TrEMBL
      G1STV1
      Related
      ENSOCUP00000006753.4
      Conserved Domains (5) summary
      COG5064
      Location:36 → 521
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:254 → 368
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:9 → 105
      IBB; Importin beta binding domain
      pfam16186
      Location:467 → 511
      Arm_3; Atypical Arm repeat
      sd00043
      Location:334 → 366
      ARM; armadillo repeat [structural motif]

    5. XM_017345332.2 → XP_017200821.1  importin subunit alpha-6 isoform X2

      UniProtKB/TrEMBL
      G1STV1
    Nucleotide Protein
    Heading Accession and Version

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