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    UBA3 ubiquitin like modifier activating enzyme 3 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100343309, updated on 8-Mar-2024

    Summary

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    Gene symbol
    UBA3
    Gene description
    ubiquitin like modifier activating enzyme 3
    See related
    Ensembl:ENSOCUG00000008169
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See UBA3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 9 NC_067382.1 (79623022..79659910)

    Chromosome 9 - NC_067382.1Genomic Context describing neighboring genes Neighboring gene leiomodin 3 Neighboring gene ARF like GTPase 6 interacting protein 5 Neighboring gene TATA element modulatory factor 1 Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Neighboring gene EGF domain specific O-linked N-acetylglucosamine transferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067382.1 Chromosome 9 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NEDD8 activating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein neddylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NEDD8-activating enzyme E1 catalytic subunit
    Names
    ubiquitin-activating enzyme 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067382.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      79623022..79659910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051851483.1 → XP_051707443.1  NEDD8-activating enzyme E1 catalytic subunit isoform X3

    2. XM_002713305.4 → XP_002713351.1  NEDD8-activating enzyme E1 catalytic subunit isoform X1

      UniProtKB/TrEMBL
      G1SUM3
      Related
      ENSOCUP00000007065.2
      Conserved Domains (3) summary
      cd01488
      Location:71 → 368
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam00899
      Location:67 → 241
      ThiF; ThiF family
      pfam08825
      Location:376 → 461
      E2_bind; E2 binding domain

    3. XM_008260916.3 → XP_008259138.1  NEDD8-activating enzyme E1 catalytic subunit isoform X2

      Conserved Domains (3) summary
      cd01488
      Location:71 → 367
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam00899
      Location:67 → 365
      ThiF; ThiF family
      pfam08825
      Location:375 → 460
      E2_bind; E2 binding domain

    4. XM_051851485.1 → XP_051707445.1  NEDD8-activating enzyme E1 catalytic subunit isoform X6

    5. XM_051851486.1 → XP_051707446.1  NEDD8-activating enzyme E1 catalytic subunit isoform X7

      UniProtKB/TrEMBL
      A0A5F9CIP5

    6. XM_002713306.4 → XP_002713352.1  NEDD8-activating enzyme E1 catalytic subunit isoform X4

      UniProtKB/TrEMBL
      A0A5F9D693
      Related
      ENSOCUP00000041699.1
      Conserved Domains (3) summary
      cd01488
      Location:57 → 354
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam00899
      Location:53 → 227
      ThiF; ThiF family
      pfam08825
      Location:362 → 447
      E2_bind; E2 binding domain

    7. XM_051851484.1 → XP_051707444.1  NEDD8-activating enzyme E1 catalytic subunit isoform X5

    Nucleotide Protein
    Heading Accession and Version

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