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    EDA ectodysplasin A [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100340021, updated on 8-Mar-2024

    Summary

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    Gene symbol
    EDA
    Gene description
    ectodysplasin A
    See related
    Ensembl:ENSOCUG00000015594
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See EDA in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) X NC_067395.1 (48228886..48586445)

    Chromosome X - NC_067395.1Genomic Context describing neighboring genes Neighboring gene NALCN channel auxiliary factor 2 Neighboring gene cytosolic iron-sulfur assembly component 2B-like Neighboring gene ubiquitin thioesterase OTUB1-like Neighboring gene uncharacterized LOC127485079 Neighboring gene forkhead box protein H1-like Neighboring gene uncharacterized LOC103351858 Neighboring gene microRNA mir-676 Neighboring gene acyl-CoA wax alcohol acyltransferase 2 Neighboring gene OTU deubiquitinase 6A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067395.1 Chromosome X Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables death receptor agonist activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables death receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ectodysplasin-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067395.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      48228886..48586445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017349960.2 → XP_017205449.1  ectodysplasin-A isoform X4

    2. XM_008272739.3 → XP_008270961.1  ectodysplasin-A isoform X3

      Conserved Domains (1) summary
      cl00147
      Location:246 → 366
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    3. XM_002720063.4 → XP_002720109.1  ectodysplasin-A isoform X1

      Conserved Domains (1) summary
      cd00184
      Location:246 → 380
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    4. XM_008272738.3 → XP_008270960.1  ectodysplasin-A isoform X2

      UniProtKB/TrEMBL
      G1T9S6
      Related
      ENSOCUP00000013397.3
      Conserved Domains (1) summary
      cd00184
      Location:246 → 378
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
    Nucleotide Protein
    Heading Accession and Version

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