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    TBXAS1 thromboxane A synthase 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100339354, updated on 10-Oct-2024

    Summary

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    Gene symbol
    TBXAS1
    Gene description
    thromboxane A synthase 1
    See related
    Ensembl:ENSOCUG00000016140
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See TBXAS1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259215.1 (1471807..1710649)

    NW_026259215.1Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 2 member L Neighboring gene homeodomain interacting protein kinase 2 Neighboring gene uncharacterized LOC127488083 Neighboring gene uncharacterized LOC127488086 Neighboring gene uncharacterized LOC127488080 Neighboring gene uncharacterized LOC127488084 Neighboring gene ubiquitin-like-conjugating enzyme ATG3 Neighboring gene poly(ADP-ribose) polymerase family member 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026259215 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase. Lee JJ, et al. Arch Pharm Res, 2010 Mar. PMID 20361303
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results point to a cellular mechanism for the antiplatelet activity of paclitaxel through the inhibition of TXA(2) synthase and cytosolic calcium mobilization.
      Title: The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables thromboxane-A synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thromboxane-A synthase
    Names
    thromboxane A synthase 1 (platelet)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NW_026259215.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      1471807..1710649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051835662.1 → XP_051691622.1  thromboxane-A synthase isoform X2

      UniProtKB/TrEMBL
      A0A5F9CDN3

    2. XM_051835661.1 → XP_051691621.1  thromboxane-A synthase isoform X1

    Nucleotide Protein
    Heading Accession and Version

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