U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    WNK3 WNK lysine deficient protein kinase 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 100337119, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    WNK3provided by VGNC
    Official Full Name
    WNK lysine deficient protein kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:36951
    See related
    BGD:BT27002; Ensembl:ENSBTAG00000023182
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: X
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (91668403..91859374, complement)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene tropomyosin alpha-4 chain-like Neighboring gene family with sequence similarity 120C Neighboring gene uncharacterized LOC132344323 Neighboring gene small nucleolar RNA SNORD52 Neighboring gene TSR2 ribosome maturation factor Neighboring gene FYVE, RhoGEF and PH domain containing 1 Neighboring gene ras-related protein Rab-21

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chloride channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of sodium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein kinase WNK3
    NP_001243516.1
    XP_024843493.1
    XP_024843494.1
    XP_059739250.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256587.1 → NP_001243516.1  serine/threonine-protein kinase WNK3

      See identical proteins and their annotated locations for NP_001243516.1

      Status: INFERRED

      Source sequence(s)
      NKLS02000030
      UniProtKB/TrEMBL
      A0AAA9T3K7
      Related
      ENSBTAP00000093384.1, ENSBTAT00000090129.1
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      91668403..91859374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987725.2 → XP_024843493.1  serine/threonine-protein kinase WNK3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T3K7
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    2. XM_024987726.2 → XP_024843494.1  serine/threonine-protein kinase WNK3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T3K7
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    3. XM_059883267.1 → XP_059739250.1  serine/threonine-protein kinase WNK3 isoform X2

      UniProtKB/TrEMBL
      A0AAA9T3K7
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials