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    MIR550-2 microRNA mir-550-2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 100316529, updated on 13-Apr-2024

    Summary

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    Gene symbol
    MIR550-2
    Gene description
    microRNA mir-550-2
    See related
    miRBase:MI0008766
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    MIR550A2; ptr-mir-550-2
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

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    See MIR550-2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (35467002..35467097, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) Unplaced Scaffold NW_026545989.1 (178795..178890)

    Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134810421 Neighboring gene proline rich 15 Neighboring gene thymosin beta-4-like Neighboring gene putative C-mannosyltransferase DPY19L2P2 Neighboring gene WAS/WASL interacting protein family member 3 Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Computational identification of novel microRNA homologs in the chimpanzee genome. Baev V, et al. Comput Biol Chem, 2009 Feb. PMID 18760970
    2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • microRNA 550-2
    • microRNA 550a-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_035898.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      JAQQLN020000006

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      35467002..35467097 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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