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    MIR545 microRNA mir-545 [ Equus caballus (horse) ]

    Gene ID: 100314956, updated on 15-Aug-2024

    Summary

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    Gene symbol
    MIR545
    Gene description
    microRNA mir-545
    See related
    Ensembl:ENSECAG00000026036 miRBase:MI0012981
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    eca-mir-545
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

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    See MIR545 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) X NC_009175.3 (58620584..58620689, complement)

    Chromosome X - NC_009175.3Genomic Context describing neighboring genes Neighboring gene microRNA mir-374b Neighboring gene microRNA mir-421 Neighboring gene microRNA mir-374a Neighboring gene zinc finger CCHC-type containing 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009175.3 Chromosome X Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In silico detection and characteristics of novel microRNA genes in the Equus caballus genome using an integrated ab initio and comparative genomic approach. Zhou M, et al. Genomics, 2009 Aug. PMID 19406225
    2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • microRNA 545

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_033109.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      PJAA01000001
      Related
      ENSECAT00000028048.2

    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009175.3 Reference EquCab3.0 Primary Assembly

      Range
      58620584..58620689 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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