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    STING1 stimulator of interferon response cGAMP interactor 1 [ Sus scrofa (pig) ]

    Gene ID: 100217389, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STING1provided by VGNC
    Official Full Name
    stimulator of interferon response cGAMP interactor 1provided by VGNC
    Primary source
    VGNC:VGNC:93547
    See related
    Ensembl:ENSSSCG00000014349
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    STING; TMEM173
    Expression
    Ubiquitous expression in lung (RPKM 19.6), spleen (RPKM 10.4) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See STING1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 2 NC_010444.4 (141359402..141367222, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 2 NC_010444.3 (147169469..147177263, complement)

    Chromosome 2 - NC_010444.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110259781 Neighboring gene endothelial cell surface expressed chemotaxis and apoptosis regulator Neighboring gene ubiquitin conjugating enzyme E2 D2 Neighboring gene CXXC finger protein 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the cloning and characterization of porcine STING (poSTING)
      Title: Molecular cloning and functional characterization of porcine stimulator of interferon genes (STING).
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2',3'-cyclic GMP-AMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclic-di-GMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of type I interferon production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in reticulophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in autophagosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stimulator of interferon genes protein
    Names
    transmembrane protein 173

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142838.1 → NP_001136310.1  stimulator of interferon genes protein

      See identical proteins and their annotated locations for NP_001136310.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ455509
      UniProtKB/Swiss-Prot
      B8XX90
      UniProtKB/TrEMBL
      A0A480PUE6
      Conserved Domains (1) summary
      pfam15009
      Location:44 → 337
      TMEM173; Transmembrane protein 173

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010444.4 Reference Sscrofa11.1 Primary Assembly

      Range
      141359402..141367222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021077058.1 → XP_020932717.1  stimulator of interferon genes protein isoform X3

      UniProtKB/TrEMBL
      A0A8D1CUC6, F1RGH2
      Related
      ENSSSCP00000015264.4, ENSSSCT00000015677.5
      Conserved Domains (1) summary
      pfam15009
      Location:106 → 399
      TMEM173; Transmembrane protein 173

    2. XM_005661703.3 → XP_005661760.2  stimulator of interferon genes protein isoform X2

      UniProtKB/TrEMBL
      A0A4X1VF02
      Conserved Domains (1) summary
      pfam15009
      Location:110 → 403
      TMEM173; Transmembrane protein 173

    3. XM_013995171.2 → XP_013850625.2  stimulator of interferon genes protein isoform X8

      UniProtKB/TrEMBL
      A0A480PUE6
      Conserved Domains (1) summary
      pfam15009
      Location:49 → 342
      TMEM173; Transmembrane protein 173

    4. XM_013995169.2 → XP_013850623.2  stimulator of interferon genes protein isoform X6

      UniProtKB/TrEMBL
      A0A8D0ZTL5
      Conserved Domains (1) summary
      pfam15009
      Location:79 → 372
      TMEM173; Transmembrane protein 173

    5. XM_013995170.2 → XP_013850624.2  stimulator of interferon genes protein isoform X7

      UniProtKB/TrEMBL
      A0A480PUE6
      Conserved Domains (1) summary
      pfam15009
      Location:70 → 363
      TMEM173; Transmembrane protein 173

    6. XM_013995168.2 → XP_013850622.2  stimulator of interferon genes protein isoform X5

      UniProtKB/TrEMBL
      A0A480PUE6
      Conserved Domains (1) summary
      pfam15009
      Location:84 → 377
      TMEM173; Transmembrane protein 173

    7. XM_013995167.2 → XP_013850621.2  stimulator of interferon genes protein isoform X4

      UniProtKB/TrEMBL
      A0A480PUE6
      Conserved Domains (1) summary
      pfam15009
      Location:88 → 381
      TMEM173; Transmembrane protein 173

    8. XM_005661704.2 → XP_005661761.2  stimulator of interferon genes protein isoform X1

      UniProtKB/TrEMBL
      A0A480PUE6
      Conserved Domains (1) summary
      pfam15009
      Location:44 → 337
      TMEM173; Transmembrane protein 173
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B8XX90.1 GenPept UniProtKB/Swiss-Prot:B8XX90

    Gene LinkOut

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