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    SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [ Sus scrofa (pig) ]

    Gene ID: 100188905, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMARCA1provided by VGNC
    Official Full Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1provided by VGNC
    Primary source
    VGNC:VGNC:93225
    See related
    Ensembl:ENSSSCG00000012649
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in kidney (RPKM 24.2), ovary (RPKM 19.8) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See SMARCA1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (106039961..106116156, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (121756253..121832168, complement)

    Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110257857 Neighboring gene centrin-2-like Neighboring gene OCRL inositol polyphosphate-5-phosphatase Neighboring gene apelin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manipulation of SMARCA2 and SMARCA4 transcript levels in porcine embryos differentially alters development and expression of SMARCA1, SOX2, NANOG, and EIF1. Magnani L, et al. Reproduction, 2009 Jan. PMID 18845624
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable global transcription activator SNF2L1
    Names
    SNF2L-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

      Range
      106039961..106116156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003135362.5 → XP_003135410.1  probable global transcription activator SNF2L1 isoform X1

      UniProtKB/TrEMBL
      A0A480JFY5, A0A4X1W9M8, A0A8D0VVK5
      Conserved Domains (7) summary
      PLN03142
      Location:90 → 1072
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd00046
      Location:206 → 345
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:862 → 901
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00271
      Location:488 → 615
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:761 → 841
      HAND; HAND
      pfam09111
      Location:916 → 1028
      SLIDE; SLIDE
      pfam13892
      Location:87 → 113
      DBINO; DNA-binding domain

    2. XM_021080851.1 → XP_020936510.1  probable global transcription activator SNF2L1 isoform X11

      UniProtKB/TrEMBL
      A0A8D0T5P6, A0A8D0VYB1, F1RTI9
      Related
      ENSSSCP00000013448.5, ENSSSCT00000013830.5
      Conserved Domains (1) summary
      cl26465
      Location:63 → 1020
      SNF2_N; SNF2 family N-terminal domain

    3. XM_005673893.3 → XP_005673950.1  probable global transcription activator SNF2L1 isoform X4

      UniProtKB/TrEMBL
      A0A8D0VVK5, A0A8D1TVE6, K7GNV1
      Related
      ENSSSCP00000029556.4, ENSSSCT00000032734.4
      Conserved Domains (8) summary
      smart00717
      Location:860 → 901
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00046
      Location:206 → 345
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:862 → 901
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00176
      Location:189 → 469
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:488 → 615
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:761 → 841
      HAND; HAND
      pfam09111
      Location:916 → 1028
      SLIDE; SLIDE
      pfam13892
      Location:87 → 113
      DBINO; DNA-binding domain

    4. XM_005673891.3 → XP_005673948.1  probable global transcription activator SNF2L1 isoform X3

      See identical proteins and their annotated locations for XP_005673948.1

      UniProtKB/TrEMBL
      A0A8D0VVK5
      Conserved Domains (8) summary
      smart00717
      Location:860 → 901
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00046
      Location:206 → 345
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:862 → 901
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00176
      Location:189 → 469
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:488 → 615
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:761 → 841
      HAND; HAND
      pfam09111
      Location:916 → 1028
      SLIDE; SLIDE
      pfam13892
      Location:87 → 113
      DBINO; DNA-binding domain

    5. XM_003360443.4 → XP_003360491.1  probable global transcription activator SNF2L1 isoform X3

      See identical proteins and their annotated locations for XP_003360491.1

      UniProtKB/TrEMBL
      A0A8D0VVK5
      Conserved Domains (8) summary
      smart00717
      Location:860 → 901
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00046
      Location:206 → 345
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:862 → 901
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00176
      Location:189 → 469
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:488 → 615
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:761 → 841
      HAND; HAND
      pfam09111
      Location:916 → 1028
      SLIDE; SLIDE
      pfam13892
      Location:87 → 113
      DBINO; DNA-binding domain

    6. XM_021080854.1 → XP_020936513.1  probable global transcription activator SNF2L1 isoform X14

      UniProtKB/TrEMBL
      A0A4X1W7H3, A0A5G2R1U6, A0A8D0VVK2
      Conserved Domains (1) summary
      cl26465
      Location:90 → 1009
      SNF2_N; SNF2 family N-terminal domain

    7. XM_021080853.1 → XP_020936512.1  probable global transcription activator SNF2L1 isoform X13

      UniProtKB/TrEMBL
      A0A4X1W7H3, A0A5G2R1U6
      Related
      ENSSSCP00000071156.2, ENSSSCT00000088402.2
      Conserved Domains (1) summary
      cl26465
      Location:90 → 1009
      SNF2_N; SNF2 family N-terminal domain

    8. XM_021080850.1 → XP_020936509.1  probable global transcription activator SNF2L1 isoform X10

      UniProtKB/TrEMBL
      A0A8D0T5P6
      Conserved Domains (1) summary
      cl26465
      Location:63 → 1020
      SNF2_N; SNF2 family N-terminal domain

    9. XM_021080847.1 → XP_020936506.1  probable global transcription activator SNF2L1 isoform X7

      UniProtKB/TrEMBL
      A0A4X1W7N5, A0A8D0VWJ8
      Conserved Domains (1) summary
      cl26465
      Location:90 → 1037
      SNF2_N; SNF2 family N-terminal domain

    10. XM_021080846.1 → XP_020936505.1  probable global transcription activator SNF2L1 isoform X5

      UniProtKB/TrEMBL
      A0A8D0VWJ8
      Conserved Domains (1) summary
      cl26465
      Location:90 → 1037
      SNF2_N; SNF2 family N-terminal domain

    11. XM_013986407.2 → XP_013841861.1  probable global transcription activator SNF2L1 isoform X5

      UniProtKB/TrEMBL
      A0A8D0VWJ8
      Conserved Domains (1) summary
      cl26465
      Location:90 → 1037
      SNF2_N; SNF2 family N-terminal domain

    12. XM_003360444.4 → XP_003360492.1  probable global transcription activator SNF2L1 isoform X2

      UniProtKB/TrEMBL
      A0A4X1W2H5, A0A8D0VWJ8, K7GLQ2
      Related
      ENSSSCP00000028784.3, ENSSSCT00000033549.3
      Conserved Domains (7) summary
      PLN03142
      Location:90 → 1060
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd00046
      Location:206 → 345
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:850 → 889
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00271
      Location:488 → 603
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:749 → 829
      HAND; HAND
      pfam09111
      Location:904 → 1016
      SLIDE; SLIDE
      pfam13892
      Location:87 → 113
      DBINO; DNA-binding domain

    13. XM_021080848.1 → XP_020936507.1  probable global transcription activator SNF2L1 isoform X9

      UniProtKB/TrEMBL
      A0A4X1W2J9, A0A8D0T5P6
      Related
      ENSSSCP00000071905.1, ENSSSCT00000071106.1
      Conserved Domains (1) summary
      cl26465
      Location:63 → 1031
      SNF2_N; SNF2 family N-terminal domain

    14. XM_005673895.3 → XP_005673952.1  probable global transcription activator SNF2L1 isoform X6

      UniProtKB/TrEMBL
      A0A8D0T5P6
      Conserved Domains (7) summary
      PLN03142
      Location:63 → 1043
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd00046
      Location:177 → 316
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:833 → 872
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00271
      Location:459 → 586
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:732 → 812
      HAND; HAND
      pfam09111
      Location:887 → 999
      SLIDE; SLIDE
      pfam13892
      Location:66 → 84
      DBINO; DNA-binding domain

    15. XM_021080855.1 → XP_020936514.1  probable global transcription activator SNF2L1 isoform X15

      UniProtKB/TrEMBL
      A0A8D0T5P6
      Conserved Domains (1) summary
      cl26465
      Location:63 → 991
      SNF2_N; SNF2 family N-terminal domain

    16. XM_021080852.1 → XP_020936511.1  probable global transcription activator SNF2L1 isoform X12

      UniProtKB/TrEMBL
      A0A8D0VVK2
      Conserved Domains (1) summary
      cl26465
      Location:90 → 1020
      SNF2_N; SNF2 family N-terminal domain

    17. XM_005673896.3 → XP_005673953.1  probable global transcription activator SNF2L1 isoform X8

      UniProtKB/TrEMBL
      A0A8D0VVK2
      Conserved Domains (7) summary
      PLN03142
      Location:90 → 1032
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd00046
      Location:206 → 345
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:822 → 861
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00271
      Location:488 → 615
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:721 → 801
      HAND; HAND
      pfam09111
      Location:876 → 988
      SLIDE; SLIDE
      pfam13892
      Location:87 → 113
      DBINO; DNA-binding domain
    Nucleotide Protein
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