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    ABCC8 ATP binding cassette subfamily C member 8 [ Sus scrofa (pig) ]

    Gene ID: 100158245, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ABCC8provided by VGNC
    Official Full Name
    ATP binding cassette subfamily C member 8provided by VGNC
    Primary source
    VGNC:VGNC:84959
    See related
    Ensembl:ENSSSCG00000013378
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    SUR1
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human mouse all
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    Genomic context

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    See ABCC8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 2 NC_010444.4 (41666974..41754624)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 2 NC_010444.3 (44725495..44812691)

    Chromosome 2 - NC_010444.4Genomic Context describing neighboring genes Neighboring gene otogelin Neighboring gene USH1 protein network component harmonin Neighboring gene potassium inwardly rectifying channel subfamily J member 11 Neighboring gene nucleobindin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Function and expression of sulfonylurea, adrenergic, and glucagon-like peptide 1 receptors in isolated porcine islets. Kelly AC, et al. Xenotransplantation, 2014 Jul-Aug. PMID 24801676, Free PMC Article
    2. K ATP channels in pig and human intracranial arteries. Ploug KB, et al. Eur J Pharmacol, 2008 Dec 28. PMID 18996111
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sulfonylurea receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: ATP-binding cassette sub-family C member 8
    Names
    ATP-binding cassette, sub-family C (CFTR/MRP), member 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010444.4 Reference Sscrofa11.1 Primary Assembly

      Range
      41666974..41754624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005661102.3 → XP_005661159.2  LOW QUALITY PROTEIN: ATP-binding cassette sub-family C member 8

      UniProtKB/TrEMBL
      A0A8D1L4C9, F1S9A6
      Related
      ENSSSCP00000014217.4, ENSSSCT00000014612.4
      Conserved Domains (1) summary
      cl26602
      Location:224 → 1579
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials