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    IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha [ Sus scrofa (pig) ]

    Gene ID: 100157242, updated on 8-Mar-2024

    Summary

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    Gene symbol
    IDH3A
    Gene description
    isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
    See related
    Ensembl:ENSSSCG00000032498
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in heart (RPKM 138.8), psoas major muscle (RPKM 99.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See IDH3A in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (47759436..47778948, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (53312283..53330719, complement)

    Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene SKI8 subunit of superkiller complex Neighboring gene DnaJ heat shock protein family (Hsp40) member A4 Neighboring gene uncharacterized LOC110261541 Neighboring gene acyl-CoA synthetase bubblegum family member 1 Neighboring gene calcium and integrin binding family member 2 Neighboring gene SH2 domain containing 7 Neighboring gene TBC1 domain family member 2B Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Subunit location and sequences of the cysteinyl peptides of pig heart NAD-dependent isocitrate dehydrogenase. Huang YC, et al. Biochemistry, 1990 Sep 11. PMID 2252888
    2. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables isocitrate dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in isocitrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
    Names
    Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
    Isocitric dehydrogenase subunit alpha
    NAD(+)-specific ICDH subunit alpha
    isocitrate dehydrogenase (NAD(+)) 3 alpha
    isocitrate dehydrogenase 3 (NAD(+)) alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

      Range
      47759436..47778948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001927338.5 → XP_001927373.4  isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

      UniProtKB/TrEMBL
      A0A480S312, A0A4X1UTC7, A0A8D1NGC5
      Related
      ENSSSCP00000081137.1, ENSSSCT00000094590.1
      Conserved Domains (1) summary
      TIGR00175
      Location:29 → 362
      mito_nad_idh; isocitrate dehydrogenase, NAD-dependent, mitochondrial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56471.2 GenPept UniProtKB/Swiss-Prot:P56471

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