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    ACVR1C activin A receptor type 1C [ Sus scrofa (pig) ]

    Gene ID: 100156756, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ACVR1Cprovided by VGNC
    Official Full Name
    activin A receptor type 1Cprovided by VGNC
    Primary source
    VGNC:VGNC:95873
    See related
    Ensembl:ENSSSCG00000015873
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in subcutaneous adipose (RPKM 7.8) and lung (RPKM 0.4) See more
    Orthologs
    human mouse all
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    Genomic context

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    See ACVR1C in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 15 NC_010457.5 (64452632..64529329, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 15 NC_010457.4 (71381954..71455690, complement)

    Chromosome 15 - NC_010457.5Genomic Context describing neighboring genes Neighboring gene ermin Neighboring gene cytohesin 1 interacting protein Neighboring gene uncharacterized LOC106506249 Neighboring gene uncharacterized LOC102166560 Neighboring gene cytochrome c pseudogene Neighboring gene activin A receptor type 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables activin receptor activity, type I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of activin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    activin receptor type-1C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010457.5 Reference Sscrofa11.1 Primary Assembly

      Range
      64452632..64529329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003133418.5 → XP_003133466.3  activin receptor type-1C isoform X2

      UniProtKB/TrEMBL
      A0A287AAP7, A0A4X1VK36, A0A8D0JE47, A0A8D1ZSH9
      Related
      ENSSSCP00000040883.1, ENSSSCT00000060597.1
      Conserved Domains (4) summary
      cd14143
      Location:201 → 488
      STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
      pfam01064
      Location:28 → 102
      Activin_recp; Activin types I and II receptor domain
      pfam07714
      Location:197 → 480
      Pkinase_Tyr; Protein tyrosine kinase
      pfam08515
      Location:168 → 195
      TGF_beta_GS; Transforming growth factor beta type I GS-motif

    2. XM_013984145.2 → XP_013839599.1  activin receptor type-1C isoform X3

      UniProtKB/TrEMBL
      A0A4X1VK36
      Conserved Domains (4) summary
      cd14143
      Location:149 → 436
      STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
      pfam07714
      Location:145 → 428
      Pkinase_Tyr; Protein tyrosine kinase
      pfam08515
      Location:116 → 143
      TGF_beta_GS; Transforming growth factor beta type I GS-motif
      cl10471
      Location:4 → 50
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    3. XM_013984144.2 → XP_013839598.1  activin receptor type-1C isoform X1

      UniProtKB/TrEMBL
      A0A4X1VK36, A0A4X1VP75
      Conserved Domains (4) summary
      cd14143
      Location:206 → 493
      STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
      pfam01064
      Location:33 → 107
      Activin_recp; Activin types I and II receptor domain
      pfam07714
      Location:202 → 485
      Pkinase_Tyr; Protein tyrosine kinase
      pfam08515
      Location:173 → 200
      TGF_beta_GS; Transforming growth factor beta type I GS-motif
    Nucleotide Protein
    Heading Accession and Version

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