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    BMP6 bone morphogenetic protein 6 [ Sus scrofa (pig) ]

    Gene ID: 100155536, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BMP6provided by VGNC
    Official Full Name
    bone morphogenetic protein 6provided by VGNC
    Primary source
    VGNC:VGNC:85845
    See related
    Ensembl:ENSSSCG00000001027
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in ovary (RPKM 13.7), lung (RPKM 9.3) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See BMP6 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (5058817..5208868)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (5163209..5313233)

    Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110261771 Neighboring gene small nuclear ribonucleoprotein U11/U12 subunit 48 Neighboring gene uncharacterized LOC110261772 Neighboring gene thioredoxin domain containing 5 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Temporal regulation of BMP2, BMP6, BMP15, GDF9, BMPR1A, BMPR1B, BMPR2 and TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig. Paradis F, et al. Reproduction, 2009 Jul. PMID 19359354
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Report temporal regulation of BMP6 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
      Title: Temporal regulation of BMP2, BMP6, BMP15, GDF9, BMPR1A, BMPR1B, BMPR2 and TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bone morphogenetic protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168001.1 → NP_001161473.1  bone morphogenetic protein 6 precursor

      See identical proteins and their annotated locations for NP_001161473.1

      Status: PROVISIONAL

      Source sequence(s)
      GU074521
      UniProtKB/TrEMBL
      A0A8D0Y610, D0VFJ0
      Related
      ENSSSCP00000001098.2, ENSSSCT00000001120.4
      Conserved Domains (2) summary
      smart00204
      Location:405 → 506
      TGFB; Transforming growth factor-beta (TGF-beta) family
      pfam00688
      Location:61 → 355
      TGFb_propeptide; TGF-beta propeptide

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

      Range
      5058817..5208868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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