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    GNB3 G protein subunit beta 3 [ Sus scrofa (pig) ]

    Gene ID: 100154522, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GNB3provided by VGNC
    Official Full Name
    G protein subunit beta 3provided by VGNC
    Primary source
    VGNC:VGNC:88532
    See related
    Ensembl:ENSSSCG00000000682
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in heart (RPKM 2.3), subcutaneous adipose (RPKM 0.4) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See GNB3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (63863656..63871352, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (66299162..66306064, complement)

    Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 5 Neighboring gene cell division cycle associated 3 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene G protein-coupled receptor 162

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of heterotrimeric G-protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
    Names
    guanine nucleotide binding protein (G protein), beta polypeptide 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243493.1 → NP_001230422.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

      Status: VALIDATED

      Source sequence(s)
      AK349471
      UniProtKB/TrEMBL
      A0A4X1UWF6
      Related
      ENSSSCP00000000727.2, ENSSSCT00000000743.4
      Conserved Domains (3) summary
      COG2319
      Location:49 → 340
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:48 → 340
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:58 → 95
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

      Range
      63863656..63871352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013987271.2 → XP_013842725.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1

      UniProtKB/TrEMBL
      A0A4X1UWF6, A0A4X1UYE5, A0A8D1V493, F1SLU8
      Conserved Domains (3) summary
      COG2319
      Location:49 → 340
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:48 → 340
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:58 → 95
      7WD40; WD40 repeat [structural motif]

    2. XM_013987274.1 → XP_013842728.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X2

      Conserved Domains (3) summary
      COG2319
      Location:101 → 337
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:105 → 337
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:143 → 178
      7WD40; WD40 repeat [structural motif]

    3. XM_013987277.1 → XP_013842731.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X3

      Conserved Domains (3) summary
      COG2319
      Location:70 → 306
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:74 → 306
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:112 → 147
      7WD40; WD40 repeat [structural motif]

    4. XM_013987280.1 → XP_013842734.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X4

      UniProtKB/TrEMBL
      A0A4X1UWF6
      Conserved Domains (3) summary
      COG2319
      Location:5 → 296
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:4 → 296
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:14 → 51
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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