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    NR2F2 nuclear receptor subfamily 2 group F member 2 [ Sus scrofa (pig) ]

    Gene ID: 100153983, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NR2F2provided by VGNC
    Official Full Name
    nuclear receptor subfamily 2 group F member 2provided by VGNC
    Primary source
    VGNC:VGNC:90881
    See related
    Ensembl:ENSSSCG00000002254
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in kidney (RPKM 26.1), ovary (RPKM 24.8) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See NR2F2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (83076119..83090250, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (88960806..88972751, complement)

    Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106504490 Neighboring gene arrestin domain containing 4 Neighboring gene microtubule-associated protein tau-like Neighboring gene atherin-like Neighboring gene uncharacterized LOC110261613 Neighboring gene uncharacterized LOC106507726

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables retinoic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    COUP transcription factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190252.1 → NP_001177181.1  COUP transcription factor 2 isoform 1

      See identical proteins and their annotated locations for NP_001177181.1

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      DN101661, DY411263, EU822301
      UniProtKB/TrEMBL
      A0A4X1ULS2, A0A8D0JKJ6, F1SCJ6, F6Q4U7
      Related
      ENSSSCP00000002448.4, ENSSSCT00000002510.5
      Conserved Domains (2) summary
      cd06948
      Location:177 → 411
      NR_LBD_COUP-TF; Ligand binding domain of chicken ovalbumin upstream promoter transcription factors, a member of the nuclear receptor family
      cd06958
      Location:79 → 151
      NR_DBD_COUP_TF; DNA-binding domain of chicken ovalbumin upstream promoter transcription factors (COUP-TFs) is composed of two C4-type zinc fingers

    2. NM_001190253.1 → NP_001177182.1  COUP transcription factor 2 isoform 2

      See identical proteins and their annotated locations for NP_001177182.1

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      EU822301
      UniProtKB/TrEMBL
      A0A4X1UL52, A0A8D0VU29, A0A8D1F517, B5A7P0
      Related
      ENSSSCP00000048884.1, ENSSSCT00000058785.3
      Conserved Domains (1) summary
      cd06948
      Location:44 → 278
      NR_LBD_COUP-TF; Ligand binding domain of chicken ovalbumin upstream promoter transcription factors, a member of the nuclear receptor family

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

      Range
      83076119..83090250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013989100.2 → XP_013844554.1  COUP transcription factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A4X1UHD7, A0A8D0JI77, A0A8D1F517
      Conserved Domains (1) summary
      cd06948
      Location:24 → 258
      NR_LBD_COUP-TF; Ligand binding domain of chicken ovalbumin upstream promoter transcription factors, a member of the nuclear receptor family
    Nucleotide Protein
    Heading Accession and Version

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