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    GABBR1 gamma-aminobutyric acid type B receptor subunit 1 [ Equus caballus (horse) ]

    Gene ID: 100147281, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GABBR1provided by VGNC
    Official Full Name
    gamma-aminobutyric acid type B receptor subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:56664
    See related
    Ensembl:ENSECAG00000009175
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See GABBR1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 20 NC_009163.3 (29641366..29669956, complement)

    Chromosome 20 - NC_009163.3Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily H member 1F Neighboring gene olfactory receptor family 2 subfamily H member 1 Neighboring gene myelin oligodendrocyte glycoprotein Neighboring gene ZFP57 zinc finger protein Neighboring gene nuclease-sensitive element-binding protein 1 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009163.3 Chromosome 20 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled GABA receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gamma-aminobutyric acid signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of G protein-coupled receptor heterodimeric complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-aminobutyric acid type B receptor subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009163.3 Reference EquCab3.0 Primary Assembly

      Range
      29641366..29669956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023624578.1 → XP_023480346.1  gamma-aminobutyric acid type B receptor subunit 1 isoform X1

      Conserved Domains (4) summary
      cd06366
      Location:171 → 581
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      pfam00084
      Location:107 → 157
      Sushi; Sushi repeat (SCR repeat)
      pfam10211
      Location:900 → 945
      Ax_dynein_light; Axonemal dynein light chain
      cd15291
      Location:608 → 880
      7tmC_GABA-B-R1; gamma-aminobutyric acid type B receptor subunit 1, member of the class C family of seven-transmembrane G protein-coupled receptors

    2. XM_023624580.1 → XP_023480348.1  gamma-aminobutyric acid type B receptor subunit 1 isoform X3

      UniProtKB/TrEMBL
      F6PPV0
      Related
      ENSECAP00000049330.2, ENSECAT00000071785.2
      Conserved Domains (3) summary
      cd06366
      Location:109 → 519
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      pfam10211
      Location:838 → 883
      Ax_dynein_light; Axonemal dynein light chain
      cd15291
      Location:546 → 818
      7tmC_GABA-B-R1; gamma-aminobutyric acid type B receptor subunit 1, member of the class C family of seven-transmembrane G protein-coupled receptors

    3. XM_023624581.1 → XP_023480349.1  gamma-aminobutyric acid type B receptor subunit 1 isoform X4

      UniProtKB/TrEMBL
      F6PPV0
      Related
      ENSECAP00000008175.3, ENSECAT00000010576.3
      Conserved Domains (3) summary
      cd06366
      Location:109 → 501
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      pfam10211
      Location:820 → 865
      Ax_dynein_light; Axonemal dynein light chain
      cd15291
      Location:528 → 800
      7tmC_GABA-B-R1; gamma-aminobutyric acid type B receptor subunit 1, member of the class C family of seven-transmembrane G protein-coupled receptors

    4. XM_023624579.1 → XP_023480347.1  gamma-aminobutyric acid type B receptor subunit 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F5PPR1
      Related
      ENSECAP00000050423.2, ENSECAT00000073578.2
      Conserved Domains (4) summary
      cd06366
      Location:171 → 563
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      pfam00084
      Location:107 → 157
      Sushi; Sushi repeat (SCR repeat)
      pfam10211
      Location:882 → 927
      Ax_dynein_light; Axonemal dynein light chain
      cd15291
      Location:590 → 862
      7tmC_GABA-B-R1; gamma-aminobutyric acid type B receptor subunit 1, member of the class C family of seven-transmembrane G protein-coupled receptors

    RNA

    1. XR_002802188.1 RNA Sequence

      Related
      ENSECAT00000068776.2
    Nucleotide Protein
    Heading Accession and Version

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