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    CNTFR ciliary neurotrophic factor receptor [ Equus caballus (horse) ]

    Gene ID: 100146590, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CNTFRprovided by VGNC
    Official Full Name
    ciliary neurotrophic factor receptorprovided by VGNC
    Primary source
    VGNC:VGNC:16693
    See related
    Ensembl:ENSECAG00000006176
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See CNTFR in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 23 NC_009166.3 (50295520..50335337, complement)

    Chromosome 23 - NC_009166.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111770208 Neighboring gene family with sequence similarity 219 member A Neighboring gene dynein axonemal intermediate chain 1 Neighboring gene energy homeostasis associated Neighboring gene ribonuclease P/MRP subunit p25 like Neighboring gene dynactin subunit 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009166.3 Chromosome 23 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ciliary neurotrophic factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ciliary neurotrophic factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CNTFR-CLCF1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ciliary neurotrophic factor receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ciliary neurotrophic factor receptor subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009166.3 Reference EquCab3.0 Primary Assembly

      Range
      50295520..50335337 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023627501.1 → XP_023483269.1  ciliary neurotrophic factor receptor subunit alpha

      UniProtKB/TrEMBL
      F7ACW5
      Conserved Domains (2) summary
      smart00408
      Location:39 → 96
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:204 → 300
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    2. XM_014735516.2 → XP_014591002.1  ciliary neurotrophic factor receptor subunit alpha

      UniProtKB/TrEMBL
      F7ACW5
      Conserved Domains (2) summary
      smart00408
      Location:39 → 96
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:204 → 300
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    3. XM_023627499.1 → XP_023483267.1  ciliary neurotrophic factor receptor subunit alpha

      UniProtKB/TrEMBL
      F7ACW5
      Related
      ENSECAP00000058336.1, ENSECAT00000121106.1
      Conserved Domains (2) summary
      smart00408
      Location:39 → 96
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:204 → 300
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    Nucleotide Protein
    Heading Accession and Version

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