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    Ilk integrin linked kinase [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100135559, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Ilk
    Gene description
    integrin linked kinase
    See related
    Ensembl:ENSCPOG00000012519
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Also known as
    ILK1; ILK2; ILK-1; ILK-2; p59ILK
    Orthologs
    human mouse all
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    Genomic context

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    See Ilk in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947492.1 (70660466..70667153)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176348.1 (2879701..2886459, complement)

    NW_026947492.1Genomic Context describing neighboring genes Neighboring gene dynein heavy chain domain 1 Neighboring gene acidic leucine-rich nuclear phosphoprotein 32 family member E-like Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene ribosomal RNA processing 8 Neighboring gene TATA-box binding protein associated factor 10 Neighboring gene tripeptidyl peptidase 1 Neighboring gene dachsous cadherin-related 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells. Ishii T, et al. J Biol Chem, 2001 Nov 16. PMID 11560928

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin-linked protein kinase
    Names
    59 kDa serine/threonine-protein kinase
    beta-integrin-linked kinase
    NP_001166442.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001172971.1 → NP_001166442.1  integrin-linked protein kinase

      See identical proteins and their annotated locations for NP_001166442.1

      Status: PROVISIONAL

      Source sequence(s)
      AF256520
      UniProtKB/Swiss-Prot
      P57044
      Related
      ENSCPOP00000011264.2, ENSCPOT00000012638.3
      Conserved Domains (6) summary
      cd00204
      Location:28 → 140
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd14057
      Location:198 → 448
      PK_ILK; Pseudokinase domain of Integrin Linked Kinase
      pfam07714
      Location:193 → 445
      Pkinase_Tyr; Protein tyrosine kinase
      pfam12796
      Location:38 → 130
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:4 → 54
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:33 → 64
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947492.1 Reference mCavPor4.1

      Range
      70660466..70667153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P57044.1 GenPept UniProtKB/Swiss-Prot:P57044

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