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    PDE4B phosphodiesterase 4B [ Bos taurus (domestic cattle) ]

    Gene ID: 100124505, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PDE4Bprovided by VGNC
    Official Full Name
    phosphodiesterase 4Bprovided by VGNC
    Primary source
    VGNC:VGNC:32676
    See related
    BGD:BT18072; Ensembl:ENSBTAG00000008636
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    See PDE4B in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (78957188..79406811, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene SH3GL interacting endocytic adaptor 1 Neighboring gene small ribosomal subunit protein uS15-like Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized protein MGC137454 Neighboring gene leptin receptor Neighboring gene transfer RNA arginine (anticodon UCU)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC152127, MGC154987

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Names
    phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
    NP_001096016.1
    XP_059737008.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102546.1 → NP_001096016.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B

      See identical proteins and their annotated locations for NP_001096016.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133548
      UniProtKB/TrEMBL
      A2VE32
      Conserved Domains (2) summary
      pfam00233
      Location:390 → 631
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam18100
      Location:151 → 266
      PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      78957188..79406811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881025.1 → XP_059737008.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1

      UniProtKB/TrEMBL
      A2VDP8
      Related
      ENSBTAP00000052598.2, ENSBTAT00000054382.3
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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