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    SMPDL3A sphingomyelin phosphodiesterase acid like 3A [ Equus caballus (horse) ]

    Gene ID: 100072974, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMPDL3Aprovided by VGNC
    Official Full Name
    sphingomyelin phosphodiesterase acid like 3Aprovided by VGNC
    Primary source
    VGNC:VGNC:23357
    See related
    Ensembl:ENSECAG00000023408
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See SMPDL3A in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 10 NC_009153.3 (71313795..71329748)

    Chromosome 10 - NC_009153.3Genomic Context describing neighboring genes Neighboring gene cAMP-dependent protein kinase inhibitor beta Neighboring gene uncharacterized LOC111775364 Neighboring gene fatty acid binding protein 7 Neighboring gene uncharacterized LOC106782505 Neighboring gene clavesin 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009153.3 Chromosome 10 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingomyelin phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sphingomyelin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclic GMP-AMP phosphodiesterase SMPDL3A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009153.3 Reference EquCab3.0 Primary Assembly

      Range
      71313795..71329748
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014734741.2 → XP_014590227.2  cyclic GMP-AMP phosphodiesterase SMPDL3A isoform X1

      UniProtKB/TrEMBL
      A0A9L0SMQ4
      Related
      ENSECAP00000069989.1, ENSECAT00000113399.1
      Conserved Domains (1) summary
      cd00842
      Location:40 → 336
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain

    2. XM_023651008.1 → XP_023506776.1  cyclic GMP-AMP phosphodiesterase SMPDL3A isoform X2

      UniProtKB/TrEMBL
      K9K3X4
      Conserved Domains (1) summary
      cd00842
      Location:1 → 232
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version

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