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    GRM8 glutamate metabotropic receptor 8 [ Equus caballus (horse) ]

    Gene ID: 100071655, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRM8provided by VGNC
    Official Full Name
    glutamate metabotropic receptor 8provided by VGNC
    Primary source
    VGNC:VGNC:18606
    See related
    Ensembl:ENSECAG00000019015
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See GRM8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 4 NC_009147.3 (81973863..82689994, complement)

    Chromosome 4 - NC_009147.3Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene developmentally-regulated GTP-binding protein 1 pseudogene Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial pseudogene Neighboring gene uncharacterized LOC111773241 Neighboring gene microRNA mir-592 Neighboring gene uncharacterized LOC102150275 Neighboring gene zinc finger protein 800

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009147.3 Chromosome 4 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables group III metabotropic glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009147.3 Reference EquCab3.0 Primary Assembly

      Range
      81973863..82689994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023639611.1 → XP_023495379.1  metabotropic glutamate receptor 8 isoform X2

      Conserved Domains (3) summary
      cd06376
      Location:44 → 504
      PBP1_mGluR_groupIII; Ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:514 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors

    2. XM_023639609.1 → XP_023495377.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F5PN60
      Related
      ENSECAP00000049787.2, ENSECAT00000068060.2
      Conserved Domains (3) summary
      cd06376
      Location:44 → 504
      PBP1_mGluR_groupIII; Ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:514 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors

    3. XM_023639610.1 → XP_023495378.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F5PN60
      Conserved Domains (3) summary
      cd06376
      Location:44 → 504
      PBP1_mGluR_groupIII; Ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:514 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

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