U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ENG endoglin [ Equus caballus (horse) ]

    Gene ID: 100070421, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ENGprovided by VGNC
    Official Full Name
    endoglinprovided by VGNC
    Primary source
    VGNC:VGNC:17578
    See related
    Ensembl:ENSECAG00000020173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    CD105
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ENG in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 25 NC_009168.3 (31802995..31832029, complement)

    Chromosome 25 - NC_009168.3Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 9 Neighboring gene folylpolyglutamate synthase Neighboring gene uncharacterized LOC106782598 Neighboring gene uncharacterized LOC111770601 Neighboring gene adenylate kinase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_009168.3 Chromosome 25 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glycosaminoglycan binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transforming growth factor beta binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transforming growth factor beta receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables type II transforming growth factor beta receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in epithelial to mesenchymal transition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vasculogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    endoglin
    Names
    endoglin (Osler-Rendu-Weber syndrome 1)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009168.3 Reference EquCab3.0 Primary Assembly

      Range
      31802995..31832029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003364144.4 → XP_003364192.2  endoglin

      UniProtKB/TrEMBL
      A0A3Q2HJG4
      Related
      ENSECAP00000033996.2, ENSECAT00000045407.2
      Conserved Domains (2) summary
      cl26464
      Location:6 → 116
      Atrophin-1; Atrophin-1 family
      cl27758
      Location:468 → 615
      Zona_pellucida; Zona pellucida-like domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.