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    GRK5 G protein-coupled receptor kinase 5 [ Equus caballus (horse) ]

    Gene ID: 100065919, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRK5provided by VGNC
    Official Full Name
    G protein-coupled receptor kinase 5provided by VGNC
    Primary source
    VGNC:VGNC:51528
    See related
    Ensembl:ENSECAG00000023764
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See GRK5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (13156199..13370973, complement)

    Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111772977 Neighboring gene regulator of G protein signaling 10 Neighboring gene high affinity immunoglobulin epsilon receptor subunit gamma Neighboring gene uncharacterized LOC111772984 Neighboring gene peroxiredoxin 3 Neighboring gene sideroflexin 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G protein-coupled receptor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G protein-coupled receptor kinase 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009144.3 Reference EquCab3.0 Primary Assembly

      Range
      13156199..13370973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023638461.1 → XP_023494229.1  G protein-coupled receptor kinase 5 isoform X4

      UniProtKB/TrEMBL
      A0A9L0TH12
      Conserved Domains (2) summary
      cd05632
      Location:236 → 548
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:53 → 228
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    2. XM_023638436.1 → XP_023494204.1  G protein-coupled receptor kinase 5 isoform X1

      UniProtKB/TrEMBL
      A0A9L0TH12
      Conserved Domains (2) summary
      cd05632
      Location:260 → 572
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:77 → 252
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    3. XM_023638470.1 → XP_023494238.1  G protein-coupled receptor kinase 5 isoform X5

      UniProtKB/TrEMBL
      A0A3Q2H1X0, A0A9L0TH12
      Related
      ENSECAP00000027524.2, ENSECAT00000046001.2
      Conserved Domains (2) summary
      cd05632
      Location:207 → 519
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:77 → 199
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    4. XM_023638452.1 → XP_023494220.1  G protein-coupled receptor kinase 5 isoform X3

      UniProtKB/TrEMBL
      A0A3Q2H629
      Related
      ENSECAP00000029280.2, ENSECAT00000039565.2
      Conserved Domains (2) summary
      cd05632
      Location:237 → 549
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:54 → 229
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    5. XM_023638444.1 → XP_023494212.1  G protein-coupled receptor kinase 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2HXP2
      Conserved Domains (2) summary
      cd05632
      Location:241 → 553
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:58 → 233
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    6. XM_023638487.1 → XP_023494255.1  G protein-coupled receptor kinase 5 isoform X8

      UniProtKB/TrEMBL
      A0A3Q2HEN4
      Related
      ENSECAP00000089514.1, ENSECAT00000122503.1
      Conserved Domains (2) summary
      cd05632
      Location:78 → 390
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:1 → 70
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    7. XM_023638480.1 → XP_023494248.1  G protein-coupled receptor kinase 5 isoform X7

      UniProtKB/TrEMBL
      A0A3Q2HEN4
      Conserved Domains (2) summary
      cd05632
      Location:131 → 443
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:62 → 123
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    8. XM_023638474.1 → XP_023494242.1  G protein-coupled receptor kinase 5 isoform X6

      UniProtKB/TrEMBL
      A0A3Q2HEN4
      Related
      ENSECAP00000032052.2, ENSECAT00000039682.3
      Conserved Domains (2) summary
      cd05632
      Location:193 → 505
      STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
      cl02565
      Location:10 → 185
      RGS; Regulator of G protein signaling (RGS) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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