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    EDA ectodysplasin A [ Equus caballus (horse) ]

    Gene ID: 100065499, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EDAprovided by VGNC
    Official Full Name
    ectodysplasin Aprovided by VGNC
    Primary source
    VGNC:VGNC:17414
    See related
    Ensembl:ENSECAG00000026865
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See EDA in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) X NC_009175.3 (54697218..55052388)

    Chromosome X - NC_009175.3Genomic Context describing neighboring genes Neighboring gene praja ring finger ubiquitin ligase 1 Neighboring gene NALCN channel auxiliary factor 2 Neighboring gene microRNA mir-676 Neighboring gene acyl-CoA wax alcohol acyltransferase 2 Neighboring gene immunoglobulin binding protein 1 Neighboring gene diacylglycerol O-acyltransferase 2 like 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009175.3 Chromosome X Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables death receptor agonist activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables death receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ectodysplasin-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009175.3 Reference EquCab3.0 Primary Assembly

      Range
      54697218..55052388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014728950.2 → XP_014584436.2  ectodysplasin-A isoform X1

      UniProtKB/TrEMBL
      A0A9L0R425
      Related
      ENSECAP00000057199.1, ENSECAT00000083561.1
      Conserved Domains (1) summary
      cd00184
      Location:246 → 380
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    2. XM_023634102.1 → XP_023489870.1  ectodysplasin-A isoform X2

      UniProtKB/TrEMBL
      A0A9L0R425
      Conserved Domains (1) summary
      cd00184
      Location:246 → 378
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials