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    GIGYF2 GRB10 interacting GYF protein 2 [ Equus caballus (horse) ]

    Gene ID: 100064814, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GIGYF2provided by VGNC
    Official Full Name
    GRB10 interacting GYF protein 2provided by VGNC
    Primary source
    VGNC:VGNC:18339
    See related
    Ensembl:ENSECAG00000024246
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See GIGYF2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 6 NC_009149.3 (19633821..19777367)

    Chromosome 6 - NC_009149.3Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E family member 2 Neighboring gene EF-hand domain family member D1 Neighboring gene potassium inwardly rectifying channel subfamily J member 13 Neighboring gene secondary ossification center associated regulator of chondrocyte maturation Neighboring gene uncharacterized LOC111773862 Neighboring gene neuronal guanine nucleotide exchange factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009149.3 Chromosome 6 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin-like growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in proximal dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GRB10 interacting GYF protein 2; GRB10-interacting GYF protein 2
    Names
    PERQ amino acid-rich with GYF domain-containing 2-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009149.3 Reference EquCab3.0 Primary Assembly

      Range
      19633821..19777367
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023642581.1 → XP_023498349.1  GRB10-interacting GYF protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A9L0THV1
      Related
      ENSECAP00000086723.1, ENSECAT00000107929.1
      Conserved Domains (1) summary
      cd00072
      Location:533 → 588
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    2. XM_023642576.1 → XP_023498344.1  GRB10-interacting GYF protein 2 isoform X1

      UniProtKB/TrEMBL
      F6X802
      Conserved Domains (1) summary
      cd00072
      Location:533 → 588
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    3. XM_014740389.2 → XP_014595875.1  GRB10-interacting GYF protein 2 isoform X2

      UniProtKB/TrEMBL
      F6X802
      Related
      ENSECAP00000021899.3, ENSECAT00000026267.4
      Conserved Domains (1) summary
      cd00072
      Location:533 → 588
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    4. XM_023642580.1 → XP_023498348.1  GRB10-interacting GYF protein 2 isoform X3

      UniProtKB/TrEMBL
      F6X802
      Conserved Domains (1) summary
      cd00072
      Location:527 → 582
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    5. XM_014740390.2 → XP_014595876.1  GRB10-interacting GYF protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A9L0QXW6, F6X802
      Related
      ENSECAP00000056242.1, ENSECAT00000091476.1
      Conserved Domains (1) summary
      cd00072
      Location:527 → 582
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    6. XM_023642577.1 → XP_023498345.1  GRB10-interacting GYF protein 2 isoform X1

      UniProtKB/TrEMBL
      F6X802
      Conserved Domains (1) summary
      cd00072
      Location:533 → 588
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    7. XM_023642578.1 → XP_023498346.1  GRB10-interacting GYF protein 2 isoform X1

      UniProtKB/TrEMBL
      F6X802
      Conserved Domains (1) summary
      cd00072
      Location:533 → 588
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    8. XM_023642582.1 → XP_023498350.1  GRB10-interacting GYF protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A9L0SGS7
      Related
      ENSECAP00000073207.1, ENSECAT00000144239.1
      Conserved Domains (1) summary
      cd00072
      Location:315 → 370
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    9. XM_023642583.1 → XP_023498351.1  GRB10-interacting GYF protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A9L0SGS7
      Conserved Domains (1) summary
      cd00072
      Location:309 → 364
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.
    Nucleotide Protein
    Heading Accession and Version

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