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    CMTR1 cap methyltransferase 1 [ Equus caballus (horse) ]

    Gene ID: 100064496, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CMTR1provided by VGNC
    Official Full Name
    cap methyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:16655
    See related
    Ensembl:ENSECAG00000014822
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    FTSJD2
    Orthologs
    human mouse all
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    Genomic context

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    See CMTR1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 20 NC_009163.3 (38087467..38142929)

    Chromosome 20 - NC_009163.3Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 22B Neighboring gene ring finger protein 8 Neighboring gene coiled-coil domain containing 167 Neighboring gene 40S ribosomal protein S29 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009163.3 Chromosome 20 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA (nucleoside-2'-O-)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 7-methylguanosine mRNA capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
    Names
    FtsJ methyltransferase domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009163.3 Reference EquCab3.0 Primary Assembly

      Range
      38087467..38142929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023624873.1 → XP_023480641.1  cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2IJY8
      Related
      ENSECAP00000045908.2, ENSECAT00000040955.2
      Conserved Domains (4) summary
      smart00456
      Location:753 → 786
      WW; Domain with 2 conserved Trp (W) residues
      pfam01585
      Location:87 → 129
      G-patch; G-patch domain
      pfam01728
      Location:232 → 448
      FtsJ; FtsJ-like methyltransferase
      cl12015
      Location:623 → 716
      Adenylation_DNA_ligase_like; Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases

    2. XM_023624874.1 → XP_023480642.1  cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2IJY8
      Conserved Domains (4) summary
      smart00456
      Location:647 → 680
      WW; Domain with 2 conserved Trp (W) residues
      pfam01585
      Location:87 → 129
      G-patch; G-patch domain
      pfam01728
      Location:259 → 342
      FtsJ; FtsJ-like methyltransferase
      cl12015
      Location:517 → 610
      Adenylation_DNA_ligase_like; Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases
    Nucleotide Protein
    Heading Accession and Version

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