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    SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Equus caballus (horse) ]

    Gene ID: 100063025, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPTLC1provided by VGNC
    Official Full Name
    serine palmitoyltransferase long chain base subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:23559
    See related
    Ensembl:ENSECAG00000020998
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 23
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 23 NC_009166.3 (50673686..50723051)

    Chromosome 23 - NC_009166.3Genomic Context describing neighboring genes Neighboring gene protein FAM205A Neighboring gene serine/threonine-protein kinase MRCK alpha Neighboring gene uncharacterized LOC111770214 Neighboring gene receptor tyrosine kinase like orphan receptor 2 Neighboring gene uncharacterized LOC111770215 Neighboring gene nuclear factor, interleukin 3 regulated

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009166.3 Chromosome 23 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine C-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine palmitoyltransferase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009166.3 Reference EquCab3.0 Primary Assembly

      Range
      50673686..50723051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001497125.5 → XP_001497175.1  serine palmitoyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2KSK7
      Related
      ENSECAP00000025374.1, ENSECAT00000033722.2
      Conserved Domains (2) summary
      COG0156
      Location:81 → 467
      BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]
      cl18945
      Location:1 → 472
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    2. XM_005605082.3 → XP_005605139.1  serine palmitoyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2H8W9, F6TYP0
      Related
      ENSECAP00000030407.1, ENSECAT00000056418.2
      Conserved Domains (2) summary
      pfam00155
      Location:98 → 432
      Aminotran_1_2; Aminotransferase class I and II
      cl18945
      Location:1 → 418
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    Nucleotide Protein
    Heading Accession and Version

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