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    VPS41 VPS41 subunit of HOPS complex [ Equus caballus (horse) ]

    Gene ID: 100062843, updated on 17-Aug-2024

    Summary

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    Official Symbol
    VPS41provided by VGNC
    Official Full Name
    VPS41 subunit of HOPS complexprovided by VGNC
    Primary source
    VGNC:VGNC:24930
    See related
    Ensembl:ENSECAG00000006943
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See VPS41 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 4 NC_009147.3 (10171507..10350180, complement)

    Chromosome 4 - NC_009147.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111773128 Neighboring gene amphiphysin Neighboring gene POU domain, class 6, transcription factor 2-like Neighboring gene uncharacterized LOC111773129

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009147.3 Chromosome 4 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosomal vesicle fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein targeting to vacuole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of HOPS complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in late endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vacuolar protein sorting-associated protein 41 homolog
    Names
    VPS41, HOPS complex subunit
    vacuolar protein sorting 41 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009147.3 Reference EquCab3.0 Primary Assembly

      Range
      10171507..10350180 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023638942.1 → XP_023494710.1  vacuolar protein sorting-associated protein 41 homolog isoform X3

      UniProtKB/TrEMBL
      A0A3Q2LKK8, A0A5F5PYD8
      Related
      ENSECAP00000041985.2, ENSECAT00000037620.2
      Conserved Domains (3) summary
      smart00299
      Location:545 → 682
      CLH; Clathrin heavy chain repeat homology
      sd00039
      Location:112 → 143
      7WD40; WD40 repeat [structural motif]
      cd16690
      Location:761 → 815
      RING-H2_Vps41; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 41 (Vps41) and similar proteins

    2. XM_023638941.1 → XP_023494709.1  vacuolar protein sorting-associated protein 41 homolog isoform X2

      UniProtKB/TrEMBL
      A0A3Q2I5Z2, F7DLZ2
      Related
      ENSECAP00000041112.2, ENSECAT00000048439.2
      Conserved Domains (3) summary
      smart00299
      Location:549 → 686
      CLH; Clathrin heavy chain repeat homology
      sd00039
      Location:88 → 145
      7WD40; WD40 repeat [structural motif]
      cd16690
      Location:765 → 819
      RING-H2_Vps41; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 41 (Vps41) and similar proteins

    3. XM_005609089.3 → XP_005609146.1  vacuolar protein sorting-associated protein 41 homolog isoform X1

      UniProtKB/TrEMBL
      A0A3Q2IDY7
      Related
      ENSECAP00000005797.2, ENSECAT00000007842.3
      Conserved Domains (3) summary
      smart00299
      Location:571 → 708
      CLH; Clathrin heavy chain repeat homology
      sd00039
      Location:88 → 132
      7WD40; WD40 repeat [structural motif]
      cd16690
      Location:787 → 841
      RING-H2_Vps41; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 41 (Vps41) and similar proteins

    4. XM_023638943.1 → XP_023494711.1  vacuolar protein sorting-associated protein 41 homolog isoform X4

      UniProtKB/TrEMBL
      A0A9L0R0I9
      Conserved Domains (2) summary
      smart00299
      Location:571 → 708
      CLH; Clathrin heavy chain repeat homology
      sd00039
      Location:88 → 132
      7WD40; WD40 repeat [structural motif]

    5. XM_014738948.2 → XP_014594434.1  vacuolar protein sorting-associated protein 41 homolog isoform X5

      UniProtKB/TrEMBL
      A0A9L0R0I9
      Conserved Domains (3) summary
      smart00299
      Location:571 → 708
      CLH; Clathrin heavy chain repeat homology
      pfam00637
      Location:575 → 710
      Clathrin; Region in Clathrin and VPS
      sd00039
      Location:88 → 132
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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