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    MAP3K1 mitogen-activated protein kinase kinase kinase 1 [ Equus caballus (horse) ]

    Gene ID: 100061688, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAP3K1provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:19930
    See related
    Ensembl:ENSECAG00000006890
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (16281293..16355620, complement)

    Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111769749 Neighboring gene MIER family member 3 Neighboring gene SET domain containing 9 Neighboring gene uncharacterized LOC102148170 Neighboring gene uncharacterized LOC111769632

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009164.3 Chromosome 21 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009164.3 Reference EquCab3.0 Primary Assembly

      Range
      16281293..16355620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023625649.1 → XP_023481417.1  mitogen-activated protein kinase kinase kinase 1

      UniProtKB/TrEMBL
      A0A3Q2HCW2
      Related
      ENSECAP00000031224.2, ENSECAT00000038924.2
      Conserved Domains (2) summary
      cd06630
      Location:1238 → 1505
      STKc_MEKK1; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 1
      cd16494
      Location:440 → 495
      RING-CH-C4HC3_ZSWM2; RING-CH finger, H2 subclass (C4HC3-type), found in zinc finger SWIM domain-containing protein 2 (ZSWIM2) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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