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    P2RX1 purinergic receptor P2X 1 [ Equus caballus (horse) ]

    Gene ID: 100060689, updated on 17-Aug-2024

    Summary

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    Official Symbol
    P2RX1provided by VGNC
    Official Full Name
    purinergic receptor P2X 1provided by VGNC
    Primary source
    VGNC:VGNC:21106
    See related
    Ensembl:ENSECAG00000009767
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See P2RX1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (47735786..47752224, complement)

    Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene nuclear cap binding subunit 3 Neighboring gene calcium/calmodulin dependent protein kinase kinase 1 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 Neighboring gene zinc finger ZZ-type and EF-hand domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009154.3 Chromosome 11 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia. Zamboulis DE, et al. Purinergic Signal, 2013 Sep. PMID 23381684, Free PMC Article
    2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellularly ATP-gated monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables purinergic nucleotide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to ATP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P2X purinoceptor 1
    Names
    purinergic receptor P2X, ligand-gated ion channel, 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009154.3 Reference EquCab3.0 Primary Assembly

      Range
      47735786..47752224 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014728020.2 → XP_014583506.1  P2X purinoceptor 1 isoform X2

      UniProtKB/TrEMBL
      A0A9L0TFJ0, F6S8X7
      Related
      ENSECAP00000085094.1, ENSECAT00000103964.1
      Conserved Domains (1) summary
      cl02993
      Location:1 → 345
      P2X_receptor; ATP P2X receptor

    2. XM_014728014.2 → XP_014583500.1  P2X purinoceptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A9L0TES5, F6S8X7
      Related
      ENSECAP00000086752.1, ENSECAT00000101884.1
      Conserved Domains (1) summary
      TIGR00863
      Location:1 → 368
      P2X; cation transporter protein

    3. XM_014728022.2 → XP_014583508.1  P2X purinoceptor 1 isoform X3

      UniProtKB/TrEMBL
      A0A9L0SDN8
      Conserved Domains (1) summary
      cl02993
      Location:1 → 323
      P2X_receptor; ATP P2X receptor
    Nucleotide Protein
    Heading Accession and Version

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