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    DGKH diacylglycerol kinase eta [ Equus caballus (horse) ]

    Gene ID: 100060528, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DGKHprovided by VGNC
    Official Full Name
    diacylglycerol kinase etaprovided by VGNC
    Primary source
    VGNC:VGNC:17151
    See related
    Ensembl:ENSECAG00000000237
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See DGKH in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 17 NC_009160.3 (27866687..28048597, complement)

    Chromosome 17 - NC_009160.3Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 216 member B Neighboring gene TNF superfamily member 11 Neighboring gene A-kinase anchoring protein 11 Neighboring gene von Willebrand factor A domain containing 8 Neighboring gene uncharacterized LOC111768596 Neighboring gene uncharacterized LOC111768595

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009160.3 Chromosome 17 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in diacylglycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    diacylglycerol kinase eta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009160.3 Reference EquCab3.0 Primary Assembly

      Range
      27866687..28048597 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023621645.1 → XP_023477413.1  diacylglycerol kinase eta isoform X3

      UniProtKB/TrEMBL
      A0A9L0T496
      Related
      ENSECAP00000083106.1, ENSECAT00000134143.1
      Conserved Domains (6) summary
      cd09576
      Location:1165 → 1229
      SAM_DGK-eta; SAM domain of diacylglycerol kinase eta
      smart00109
      Location:272 → 317
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:788 → 945
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:358 → 480
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:200 → 249
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:91 → 187
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

    2. XM_014732111.2 → XP_014587597.1  diacylglycerol kinase eta isoform X8

      UniProtKB/TrEMBL
      A0A9L0R916, A0A9L0T496
      Related
      ENSECAP00000060517.1, ENSECAT00000100100.1
      Conserved Domains (7) summary
      cd09576
      Location:1005 → 1069
      SAM_DGK-eta; SAM domain of diacylglycerol kinase eta
      smart00109
      Location:112 → 157
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00454
      Location:1006 → 1069
      SAM; Sterile alpha motif
      smart00045
      Location:628 → 785
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:198 → 320
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:40 → 89
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cl17171
      Location:1 → 27
      PH-like; Pleckstrin homology-like domain

    3. XM_023621649.1 → XP_023477417.1  diacylglycerol kinase eta isoform X7

      UniProtKB/TrEMBL
      A0A9L0T496
      Conserved Domains (6) summary
      cd09576
      Location:1014 → 1078
      SAM_DGK-eta; SAM domain of diacylglycerol kinase eta
      smart00109
      Location:121 → 166
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:637 → 794
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:207 → 329
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:49 → 98
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cl17171
      Location:2 → 36
      PH-like; Pleckstrin homology-like domain

    4. XM_014732113.2 → XP_014587599.1  diacylglycerol kinase eta isoform X9

      Conserved Domains (2) summary
      smart00045
      Location:519 → 676
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:89 → 211
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)

    5. XM_023621644.1 → XP_023477412.1  diacylglycerol kinase eta isoform X2

      UniProtKB/TrEMBL
      A0A3Q2I3I1
      Conserved Domains (6) summary
      cd09576
      Location:1167 → 1231
      SAM_DGK-eta; SAM domain of diacylglycerol kinase eta
      smart00109
      Location:305 → 350
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:821 → 978
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:391 → 513
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:233 → 282
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:124 → 220
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

    6. XM_023621646.1 → XP_023477414.1  diacylglycerol kinase eta isoform X4

      UniProtKB/TrEMBL
      A0A9L0T496, A0A9L0TEH7
      Related
      ENSECAP00000085493.1, ENSECAT00000125055.1
      Conserved Domains (5) summary
      smart00109
      Location:305 → 350
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:821 → 978
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:391 → 513
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:233 → 282
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:124 → 220
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

    7. XM_023621643.1 → XP_023477411.1  diacylglycerol kinase eta isoform X1

      UniProtKB/TrEMBL
      A0A9L0T496
      Conserved Domains (6) summary
      cd09576
      Location:1198 → 1262
      SAM_DGK-eta; SAM domain of diacylglycerol kinase eta
      smart00109
      Location:305 → 350
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:821 → 978
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:391 → 513
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:233 → 282
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:124 → 220
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

    8. XM_023621647.1 → XP_023477415.1  diacylglycerol kinase eta isoform X5

      UniProtKB/TrEMBL
      A0A9L0T496, F7DSL9
      Related
      ENSECAP00000000554.3, ENSECAT00000000701.4
      Conserved Domains (6) summary
      cd09576
      Location:1141 → 1205
      SAM_DGK-eta; SAM domain of diacylglycerol kinase eta
      smart00109
      Location:248 → 293
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:764 → 921
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:334 → 456
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:176 → 225
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:67 → 163
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

    9. XM_023621648.1 → XP_023477416.1  diacylglycerol kinase eta isoform X6

      UniProtKB/TrEMBL
      A0A3Q2I3I1
      Conserved Domains (5) summary
      smart00109
      Location:305 → 350
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:821 → 978
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:391 → 513
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:233 → 282
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:124 → 220
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain
    Nucleotide Protein
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